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==Crystal Structure of the bromodomain of human BAZ2B in complex with compound-1 N01197==
==Crystal Structure of the bromodomain of human BAZ2B in complex with compound-1 N01197==
<StructureSection load='4nrb' size='340' side='right' caption='[[4nrb]], [[Resolution|resolution]] 2.08&Aring;' scene=''>
<StructureSection load='4nrb' size='340' side='right'caption='[[4nrb]], [[Resolution|resolution]] 2.08&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4nrb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NRB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NRB FirstGlance]. <br>
<table><tr><td colspan='2'>[[4nrb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NRB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NRB FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2LX:N-METHYL-2-(TETRAHYDRO-2H-PYRAN-4-YLOXY)BENZAMIDE'>2LX</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.08&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4nr9|4nr9]], [[4nra|4nra]], [[4nrc|4nrc]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2LX:N-METHYL-2-(TETRAHYDRO-2H-PYRAN-4-YLOXY)BENZAMIDE'>2LX</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAZ2B, KIAA1476 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nrb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nrb OCA], [https://pdbe.org/4nrb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nrb RCSB], [https://www.ebi.ac.uk/pdbsum/4nrb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nrb ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nrb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nrb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nrb RCSB], [http://www.ebi.ac.uk/pdbsum/4nrb PDBsum]</span></td></tr>
</table>
<table>
== Function ==
[https://www.uniprot.org/uniprot/BAZ2B_HUMAN BAZ2B_HUMAN] May play a role in transcriptional regulation interacting with ISWI.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4nrb" style="background-color:#fffaf0;"></div>
==See Also==
*[[Bromodomain adjacent to zinc finger 3D structures|Bromodomain adjacent to zinc finger 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Large Structures]]
[[Category: Bountra, C.]]
[[Category: Arrowsmith CH]]
[[Category: Chaikuad, A.]]
[[Category: Bountra C]]
[[Category: Ciulli, A.]]
[[Category: Chaikuad A]]
[[Category: Delft, F von.]]
[[Category: Ciulli A]]
[[Category: Edwards, A M.]]
[[Category: Edwards AM]]
[[Category: Fedorov, O.]]
[[Category: Fedorov O]]
[[Category: Felletar, I.]]
[[Category: Felletar I]]
[[Category: Ferguson, F M.]]
[[Category: Ferguson FM]]
[[Category: Filippakopoulos, P.]]
[[Category: Filippakopoulos P]]
[[Category: Knapp, S.]]
[[Category: Knapp S]]
[[Category: Muniz, J R.C.]]
[[Category: Muniz JRC]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Von Delft F]]
[[Category: Acetylated lysine binding protein]]
[[Category: Bromodomain]]
[[Category: Kiaa1476]]
[[Category: Sgc]]
[[Category: Structural genomics consortium]]
[[Category: Transcription]]
[[Category: Walp4]]

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