4npq: Difference between revisions
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==The resting-state conformation of the GLIC ligand-gated ion channel== | ==The resting-state conformation of the GLIC ligand-gated ion channel== | ||
<StructureSection load='4npq' size='340' side='right' caption='[[4npq]], [[Resolution|resolution]] 4.35Å' scene=''> | <StructureSection load='4npq' size='340' side='right'caption='[[4npq]], [[Resolution|resolution]] 4.35Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4npq]] is a 20 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4npq]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Gloeobacter_violaceus_PCC_7421 Gloeobacter violaceus PCC 7421]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NPQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NPQ FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4.35Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4npq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4npq OCA], [https://pdbe.org/4npq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4npq RCSB], [https://www.ebi.ac.uk/pdbsum/4npq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4npq ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 4npq" style="background-color:#fffaf0;"></div> | |||
==See Also== | |||
*[[Ion channels 3D structures|Ion channels 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Gloeobacter violaceus PCC 7421]] | ||
[[Category: Changeux | [[Category: Large Structures]] | ||
[[Category: Corringer | [[Category: Changeux JP]] | ||
[[Category: Delarue | [[Category: Corringer PJ]] | ||
[[Category: Haouz | [[Category: Delarue M]] | ||
[[Category: Huon | [[Category: Haouz A]] | ||
[[Category: Menny | [[Category: Huon C]] | ||
[[Category: Nemecz | [[Category: Menny A]] | ||
[[Category: Poitevin | [[Category: Nemecz A]] | ||
[[Category: Sauguet | [[Category: Poitevin F]] | ||
[[Category: Shahsavar | [[Category: Sauguet L]] | ||
[[Category: Shahsavar A]] | |||