4nm4: Difference between revisions

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==Crystal structure of broadly neutralizing antibody CR8043==
==Crystal structure of broadly neutralizing antibody CR8043==
<StructureSection load='4nm4' size='340' side='right' caption='[[4nm4]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
<StructureSection load='4nm4' size='340' side='right'caption='[[4nm4]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4nm4]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NM4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NM4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4nm4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NM4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NM4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4mn8|4mn8]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nm4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nm4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nm4 RCSB], [http://www.ebi.ac.uk/pdbsum/4nm4 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nm4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nm4 OCA], [https://pdbe.org/4nm4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nm4 RCSB], [https://www.ebi.ac.uk/pdbsum/4nm4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nm4 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/IGKC_HUMAN IGKC_HUMAN] Defects in IGKC are the cause of immunoglobulin kappa light chain deficiency (IGKCD) [MIM:[https://omim.org/entry/614102 614102]. IGKCD is a disease characterized by the complete absence of immunoglobulin kappa chains.<ref>PMID:3931219</ref>
== Function ==
[https://www.uniprot.org/uniprot/IGKC_HUMAN IGKC_HUMAN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4nm4" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Antibody|Antibody]]
*[[Antibody 3D structures|Antibody 3D structures]]
*[[Sandbox 20009|Sandbox 20009]]
*[[3D structures of human antibody|3D structures of human antibody]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Lee, P S]]
[[Category: Large Structures]]
[[Category: Wilson, I A]]
[[Category: Lee PS]]
[[Category: Antibody]]
[[Category: Wilson IA]]
[[Category: Fab]]
[[Category: Immune recognition]]
[[Category: Immune system]]
[[Category: Immunoglobulin]]
[[Category: Influenza hemagglutinin]]

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