4mz1: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
 ==Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with a Internal Deletion of CBS Domain from Campylobacter jejuni complexed with inhibitor compound P12==
-<StructureSection load='4mz1' size='340' side='right' caption='[[4mz1]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
+<StructureSection load='4mz1' size='340' side='right'caption='[[4mz1]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4mz1]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Camje Camje]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MZ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MZ1 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4mz1]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Campylobacter_jejuni_subsp._jejuni_NCTC_11168_=_ATCC_700819 Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MZ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MZ1 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2F1:1-(4-BROMOPHENYL)-3-{2-[3-(PROP-1-EN-2-YL)PHENYL]PROPAN-2-YL}UREA'>2F1</scene>, <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3991&#8491;</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">guaB, Cj1058c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=192222 CAMJE])</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2F1:1-(4-BROMOPHENYL)-3-{2-[3-(PROP-1-EN-2-YL)PHENYL]PROPAN-2-YL}UREA'>2F1</scene>, <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/IMP_dehydrogenase IMP dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.205 1.1.1.205] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mz1 OCA], [https://pdbe.org/4mz1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mz1 RCSB], [https://www.ebi.ac.uk/pdbsum/4mz1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mz1 ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mz1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mz1 RCSB], [http://www.ebi.ac.uk/pdbsum/4mz1 PDBsum]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/Q0P9J4_CAMJE Q0P9J4_CAMJE]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[HAMAP-Rule:MF_01964]
+[https://www.uniprot.org/uniprot/Q0P9J4_CAMJE Q0P9J4_CAMJE] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[HAMAP-Rule:MF_01964]
 ==See Also==
-*[[Inosine monophosphate dehydrogenase|Inosine monophosphate dehydrogenase]]
+*[[Inosine monophosphate dehydrogenase 3D structures|Inosine monophosphate dehydrogenase 3D structures]]
 __TOC__
 </StructureSection>
-[[Category: Camje]]
+[[Category: Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]]
-[[Category: IMP dehydrogenase]]
+[[Category: Large Structures]]
-[[Category: Anderson, W F]]
+[[Category: Anderson WF]]
-[[Category: Structural genomic]]
+[[Category: CSGID]]
-[[Category: Csgid]]
+[[Category: Gu M]]
-[[Category: Gu, M]]
+[[Category: Joachimiak A]]
-[[Category: Joachimiak, A]]
+[[Category: Kim Y]]
-[[Category: Kim, Y]]
+[[Category: Makowska-Grzyska M]]
-[[Category: Makowska-Grzyska, M]]
-[[Category: Alpha-beta structure]]
-[[Category: National institute of allergy and infectious disease]]
-[[Category: Niaid]]
-[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
-[[Category: Tim barrel]]