4mw7: Difference between revisions

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 ==Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(5-chloro-2-ethoxy-3-iodobenzyl)amino]propyl}-3-thiophen-3-ylurea (Chem 1469)==
-<StructureSection load='4mw7' size='340' side='right' caption='[[4mw7]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
+<StructureSection load='4mw7' size='340' side='right'caption='[[4mw7]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4mw7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_(trypanozoon)_brucei Trypanosoma (trypanozoon) brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MW7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MW7 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4mw7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MW7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MW7 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2EF:1-{3-[(5-CHLORO-2-ETHOXY-3-IODOBENZYL)AMINO]PROPYL}-3-THIOPHEN-3-YLUREA'>2EF</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75&#8491;</td></tr>
-<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2EF:1-{3-[(5-CHLORO-2-ETHOXY-3-IODOBENZYL)AMINO]PROPYL}-3-THIOPHEN-3-YLUREA'>2EF</scene>, <scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4eg1|4eg1]], [[4eg3|4eg3]], [[4eg5|4eg5]], [[4mvw|4mvw]], [[4mvx|4mvx]], [[4mvy|4mvy]], [[4mw0|4mw0]], [[4mw1|4mw1]], [[4mw2|4mw2]], [[4mw4|4mw4]], [[4mw5|4mw5]], [[4mw6|4mw6]], [[4mw9|4mw9]], [[4mwb|4mwb]], [[4mwc|4mwc]], [[4mwd|4mwd]], [[4mwe|4mwe]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mw7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mw7 OCA], [https://pdbe.org/4mw7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mw7 RCSB], [https://www.ebi.ac.uk/pdbsum/4mw7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mw7 ProSAT]</span></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Tb10.70.6470 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5691 Trypanosoma (Trypanozoon) brucei])</td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine--tRNA_ligase Methionine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.10 6.1.1.10] </span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mw7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mw7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mw7 RCSB], [http://www.ebi.ac.uk/pdbsum/4mw7 PDBsum]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q38C91_TRYB2 Q38C91_TRYB2]
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 18: / Line 18: @@
 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 4mw7" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Methionine--tRNA ligase]]
+[[Category: Large Structures]]
-[[Category: Fan, E]]
+[[Category: Trypanosoma brucei]]
-[[Category: Hol, W G.J]]
+[[Category: Fan E]]
-[[Category: Kim, J E]]
+[[Category: Hol WGJ]]
-[[Category: Koh, C Y]]
+[[Category: Kim JE]]
-[[Category: Liu, J]]
+[[Category: Koh CY]]
-[[Category: Schueren, W J.de van der]]
+[[Category: Liu J]]
-[[Category: Shibata, S]]
+[[Category: Shibata S]]
-[[Category: Verlinde, C L.M J]]
+[[Category: Verlinde CLMJ]]
-[[Category: Wetzel, A B]]
+[[Category: Wetzel AB]]
-[[Category: Zhang, Z]]
+[[Category: Zhang Z]]
-[[Category: Aar]]
+[[Category: De van der Schueren WJ]]
-[[Category: Aminoacyl-trna synthetase]]
-[[Category: Ligase-ligase inhibitor complex]]
-[[Category: Metr]]
-[[Category: Nucleotide binding]]
-[[Category: Parasite]]
-[[Category: Protein-inhibitor complex]]
-[[Category: Rossmann fold]]
-[[Category: Translation]]