4lbt: Difference between revisions

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==Endothiapepsin in complex with 100mM acylhydrazone inhibitor==
==Endothiapepsin in complex with 100mM acylhydrazone inhibitor==
<StructureSection load='4lbt' size='340' side='right' caption='[[4lbt]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
<StructureSection load='4lbt' size='340' side='right'caption='[[4lbt]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4lbt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LBT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LBT FirstGlance]. <br>
<table><tr><td colspan='2'>[[4lbt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LBT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LBT FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1TZ:(2S)-2-AZANYL-3-(3H-INDOL-3-YL)-N-[(E)-(2,4,6-TRIMETHYLPHENYL)METHYLIDENEAMINO]PROPANAMIDE'>1TZ</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.251&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3t7p|3t7p]], [[4kup|4kup]], [[4lhh|4lhh]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1TZ:(2S)-2-AZANYL-3-(3H-INDOL-3-YL)-N-[(E)-(2,4,6-TRIMETHYLPHENYL)METHYLIDENEAMINO]PROPANAMIDE'>1TZ</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endothiapepsin Endothiapepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.22 3.4.23.22] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lbt OCA], [https://pdbe.org/4lbt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lbt RCSB], [https://www.ebi.ac.uk/pdbsum/4lbt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lbt ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lbt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lbt RCSB], [http://www.ebi.ac.uk/pdbsum/4lbt PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CARP_CRYPA CARP_CRYPA]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4lbt" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
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</StructureSection>
</StructureSection>
[[Category: Cryphonectria parasitica]]
[[Category: Cryphonectria parasitica]]
[[Category: Endothiapepsin]]
[[Category: Large Structures]]
[[Category: Heine, A]]
[[Category: Heine A]]
[[Category: Klebe, G]]
[[Category: Klebe G]]
[[Category: Radeva, N]]
[[Category: Radeva N]]
[[Category: Winquist, J]]
[[Category: Winquist J]]
[[Category: Aspartic protease]]
[[Category: Hydrolase]]
[[Category: Hydrolase-hydrolase inhibitor complex]]

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