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==Crystal structure of anabolic ornithine carbamoyltransferase from Vibrio vulnificus in complex with citrulline and inorganic phosphate== | ==Crystal structure of anabolic ornithine carbamoyltransferase from Vibrio vulnificus in complex with citrulline and inorganic phosphate== | ||
<StructureSection load='4jqo' size='340' side='right' caption='[[4jqo]], [[Resolution|resolution]] 2.08Å' scene=''> | <StructureSection load='4jqo' size='340' side='right'caption='[[4jqo]], [[Resolution|resolution]] 2.08Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4jqo]] is a 3 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4jqo]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_vulnificus_CMCP6 Vibrio vulnificus CMCP6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JQO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JQO FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.082Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIR:CITRULLINE'>CIR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
<tr id=' | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jqo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jqo OCA], [https://pdbe.org/4jqo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jqo RCSB], [https://www.ebi.ac.uk/pdbsum/4jqo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jqo ProSAT]</span></td></tr> | ||
< | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/OTC_VIBVU OTC_VIBVU] Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis (By similarity). | ||
==See Also== | ==See Also== | ||
*[[Ornithine carbamoyltransferase|Ornithine carbamoyltransferase]] | *[[Ornithine carbamoyltransferase 3D structures|Ornithine carbamoyltransferase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Vibrio vulnificus | [[Category: Vibrio vulnificus CMCP6]] | ||
[[Category: Anderson | [[Category: Anderson WF]] | ||
[[Category: Domagalski MJ]] | |||
[[Category: Domagalski | [[Category: Grimshaw S]] | ||
[[Category: Grimshaw | [[Category: Minor W]] | ||
[[Category: Minor | [[Category: Shabalin IG]] | ||
[[Category: Shabalin | [[Category: Winsor J]] | ||
[[Category: Winsor | |||
Latest revision as of 18:47, 20 September 2023
Crystal structure of anabolic ornithine carbamoyltransferase from Vibrio vulnificus in complex with citrulline and inorganic phosphateCrystal structure of anabolic ornithine carbamoyltransferase from Vibrio vulnificus in complex with citrulline and inorganic phosphate
Structural highlights
FunctionOTC_VIBVU Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis (By similarity). See Also |
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