4jci: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
No edit summary
No edit summary
 
(4 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{STRUCTURE_4jci|  PDB=4jci  |  SCENE=  }}
===Crystal structure of csal_2705, a putative hydroxyproline epimerase from CHROMOHALOBACTER SALEXIGENS (TARGET EFI-506486), SPACE GROUP P212121, unliganded===


==About this Structure==
==Crystal structure of csal_2705, a putative hydroxyproline epimerase from CHROMOHALOBACTER SALEXIGENS (TARGET EFI-506486), SPACE GROUP P212121, unliganded==
[[4jci]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Chromohalobacter_salexigens_dsm_3043 Chromohalobacter salexigens dsm 3043]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JCI OCA].  
<StructureSection load='4jci' size='340' side='right'caption='[[4jci]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
[[Category: Chromohalobacter salexigens dsm 3043]]
== Structural highlights ==
[[Category: Almo, S C.]]
<table><tr><td colspan='2'>[[4jci]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Chromohalobacter_salexigens_DSM_3043 Chromohalobacter salexigens DSM 3043]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JCI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JCI FirstGlance]. <br>
[[Category: Bhosle, R.]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
[[Category: Chowdhury, S.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
[[Category: Efi]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jci OCA], [https://pdbe.org/4jci PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jci RCSB], [https://www.ebi.ac.uk/pdbsum/4jci PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jci ProSAT]</span></td></tr>
[[Category: Evans, B.]]
</table>
[[Category: Gerlt, J A.]]
== Function ==
[[Category: Glenn, A Scott.]]
[https://www.uniprot.org/uniprot/4HYPE_CHRSD 4HYPE_CHRSD] Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp). Is likely involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate. Displays no proline racemase activity.<ref>PMID:24980702</ref>
[[Category: Hammonds, J.]]
== References ==
[[Category: Hillerich, B.]]
<references/>
[[Category: Imker, H J.]]
__TOC__
[[Category: Love, J.]]
</StructureSection>
[[Category: Morisco, L L.]]
[[Category: Chromohalobacter salexigens DSM 3043]]
[[Category: Obaidi, N F.Al.]]
[[Category: Large Structures]]
[[Category: Seidel, R D.]]
[[Category: Al Obaidi NF]]
[[Category: Sojitra, S.]]
[[Category: Almo SC]]
[[Category: Stead, M.]]
[[Category: Bhosle R]]
[[Category: Toro, R.]]
[[Category: Chowdhury S]]
[[Category: Vetting, M W.]]
[[Category: Evans B]]
[[Category: Washington, E.]]
[[Category: Gerlt JA]]
[[Category: Wasserman, S R.]]
[[Category: Hammonds J]]
[[Category: Efi]]
[[Category: Hillerich B]]
[[Category: Enzyme function initiative]]
[[Category: Imker HJ]]
[[Category: Isomerase]]
[[Category: Love J]]
[[Category: Putative hydroxyproline epimerase]]
[[Category: Morisco LL]]
[[Category: Structural genomic]]
[[Category: Scott Glenn A]]
[[Category: Seidel RD]]
[[Category: Sojitra S]]
[[Category: Stead M]]
[[Category: Toro R]]
[[Category: Vetting MW]]
[[Category: Washington E]]
[[Category: Wasserman SR]]

Latest revision as of 18:40, 20 September 2023

Crystal structure of csal_2705, a putative hydroxyproline epimerase from CHROMOHALOBACTER SALEXIGENS (TARGET EFI-506486), SPACE GROUP P212121, unligandedCrystal structure of csal_2705, a putative hydroxyproline epimerase from CHROMOHALOBACTER SALEXIGENS (TARGET EFI-506486), SPACE GROUP P212121, unliganded

Structural highlights

4jci is a 2 chain structure with sequence from Chromohalobacter salexigens DSM 3043. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.7Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

4HYPE_CHRSD Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp). Is likely involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate. Displays no proline racemase activity.[1]

References

  1. ↑ Zhao S, Sakai A, Zhang X, Vetting MW, Kumar R, Hillerich B, San Francisco B, Solbiati J, Steves A, Brown S, Akiva E, Barber A, Seidel RD, Babbitt PC, Almo SC, Gerlt JA, Jacobson MP. Prediction and characterization of enzymatic activities guided by sequence similarity and genome neighborhood networks. Elife. 2014 Jun 30;3. doi: 10.7554/eLife.03275. PMID:24980702 doi:http://dx.doi.org/10.7554/eLife.03275

4jci, resolution 1.70Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=4jci&oldid=3875797"