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==Crystal structure of Ribonuclease A soaked in 40% Cyclohexanol: One of twelve in MSCS set==
==Crystal structure of Ribonuclease A soaked in 40% Cyclohexanol: One of twelve in MSCS set==
<StructureSection load='4j62' size='340' side='right' caption='[[4j62]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
<StructureSection load='4j62' size='340' side='right'caption='[[4j62]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4j62]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J62 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4J62 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4j62]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J62 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J62 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CXL:CYCLOHEXANOL'>CXL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.039&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4j5z|4j5z]], [[4j60|4j60]], [[4j61|4j61]], [[4j63|4j63]], [[4j64|4j64]], [[4j65|4j65]], [[4j66|4j66]], [[4j67|4j67]], [[4j68|4j68]], [[4j69|4j69]], [[4j6a|4j6a]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CXL:CYCLOHEXANOL'>CXL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.5 3.1.27.5] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j62 OCA], [https://pdbe.org/4j62 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j62 RCSB], [https://www.ebi.ac.uk/pdbsum/4j62 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j62 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4j62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j62 OCA], [http://pdbe.org/4j62 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4j62 RCSB], [http://www.ebi.ac.uk/pdbsum/4j62 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4j62 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RNAS1_BOVIN RNAS1_BOVIN]] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.<ref>PMID:7479688</ref>
[https://www.uniprot.org/uniprot/RNAS1_BOVIN RNAS1_BOVIN] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.<ref>PMID:7479688</ref>  


==See Also==
==See Also==
*[[Temp|Temp]]
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Pancreatic ribonuclease]]
[[Category: Large Structures]]
[[Category: Dechene, M]]
[[Category: Dechene M]]
[[Category: Kearney, B M]]
[[Category: Kearney BM]]
[[Category: Mattos, C]]
[[Category: Mattos C]]
[[Category: Swartz, P D]]
[[Category: Swartz PD]]
[[Category: Endoribonuclease]]
[[Category: Hydrolase]]

Latest revision as of 18:36, 20 September 2023

Crystal structure of Ribonuclease A soaked in 40% Cyclohexanol: One of twelve in MSCS setCrystal structure of Ribonuclease A soaked in 40% Cyclohexanol: One of twelve in MSCS set

Structural highlights

4j62 is a 1 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.039Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RNAS1_BOVIN Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.[1]

See Also

References

  1. ↑ delCardayre SB, Ribo M, Yokel EM, Quirk DJ, Rutter WJ, Raines RT. Engineering ribonuclease A: production, purification and characterization of wild-type enzyme and mutants at Gln11. Protein Eng. 1995 Mar;8(3):261-73. PMID:7479688

4j62, resolution 2.04Å

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