4ixx: Difference between revisions

No edit summary
No edit summary
 
(3 intermediate revisions by the same user not shown)
Line 1: Line 1:
==Crystal structure of S213G variant DAH7PS without Tyr bound from Neisseria meningitidis==
==Crystal structure of S213G variant DAH7PS without Tyr bound from Neisseria meningitidis==
<StructureSection load='4ixx' size='340' side='right' caption='[[4ixx]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='4ixx' size='340' side='right'caption='[[4ixx]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ixx]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Neimb Neimb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IXX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IXX FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ixx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_meningitidis_MC58 Neisseria meningitidis MC58]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IXX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IXX FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4hsn|4hsn]], [[4hso|4hso]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aroG, NMB0307 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=122586 NEIMB])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ixx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ixx OCA], [https://pdbe.org/4ixx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ixx RCSB], [https://www.ebi.ac.uk/pdbsum/4ixx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ixx ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-deoxy-7-phosphoheptulonate_synthase 3-deoxy-7-phosphoheptulonate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.54 2.5.1.54] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ixx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ixx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ixx RCSB], [http://www.ebi.ac.uk/pdbsum/4ixx PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9K169_NEIMB Q9K169_NEIMB] Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) (By similarity).[PIRNR:PIRNR001361]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 17: Line 18:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4ixx" style="background-color:#fffaf0;"></div>
==See Also==
*[[DAHP synthase 3D structures|DAHP synthase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: 3-deoxy-7-phosphoheptulonate synthase]]
[[Category: Large Structures]]
[[Category: Neimb]]
[[Category: Neisseria meningitidis MC58]]
[[Category: Allison, T M]]
[[Category: Allison TM]]
[[Category: Cochrane, F C]]
[[Category: Cochrane FC]]
[[Category: Cross, P J]]
[[Category: Cross PJ]]
[[Category: Parker, E J]]
[[Category: Parker EJ]]
[[Category: Pietersma, A L]]
[[Category: Pietersma AL]]
[[Category: Wilson-Coutts, S M]]
[[Category: Wilson-Coutts SM]]
[[Category: Allosteric regulation]]
[[Category: Aromatic biosynthesis]]
[[Category: Dah7p]]
[[Category: Dahp]]
[[Category: Shikimate pathway]]
[[Category: Tim barrel]]
[[Category: Tim-barrel]]
[[Category: Transferase]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA