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==Structure of the Flavoprotein Tryptophan-2-Monooxygenase==
==Structure of the Flavoprotein Tryptophan-2-Monooxygenase==
<StructureSection load='4iv9' size='340' side='right' caption='[[4iv9]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='4iv9' size='340' side='right'caption='[[4iv9]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4iv9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_savastanoi Pseudomonas savastanoi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IV9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IV9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4iv9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_savastanoi Pseudomonas savastanoi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IV9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IV9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TSR:2-(1H-INDOL-3-YL)ACETAMIDE'>TSR</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.951&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">iaaM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=29438 Pseudomonas savastanoi])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TSR:2-(1H-INDOL-3-YL)ACETAMIDE'>TSR</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tryptophan_2-monooxygenase Tryptophan 2-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.12.3 1.13.12.3] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4iv9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iv9 OCA], [https://pdbe.org/4iv9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4iv9 RCSB], [https://www.ebi.ac.uk/pdbsum/4iv9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4iv9 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4iv9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iv9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4iv9 RCSB], [http://www.ebi.ac.uk/pdbsum/4iv9 PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TR2M_PSESS TR2M_PSESS]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4iv9" style="background-color:#fffaf0;"></div>
==See Also==
*[[Monooxygenase 3D structures|Monooxygenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Pseudomonas savastanoi]]
[[Category: Pseudomonas savastanoi]]
[[Category: Tryptophan 2-monooxygenase]]
[[Category: Fitzpatrick PF]]
[[Category: Fitzpatrick, P F]]
[[Category: Gaweska HM]]
[[Category: Gaweska, H M]]
[[Category: Hart PJ]]
[[Category: Hart, P J]]
[[Category: Taylor AB]]
[[Category: Taylor, A B]]
[[Category: Fad cofactor]]
[[Category: Flavoenzyme]]
[[Category: Indole-3-acetamide]]
[[Category: Monoamine oxidase family]]
[[Category: Oxidative decarboxylation]]
[[Category: Oxidoreductase]]

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