4iv3: Difference between revisions
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<StructureSection load='4iv3' size='340' side='right'caption='[[4iv3]], [[Resolution|resolution]] 2.90Å' scene=''> | <StructureSection load='4iv3' size='340' side='right'caption='[[4iv3]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4iv3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[4iv3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Foot-and-mouth_disease_virus_A Foot-and-mouth disease virus A]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IV3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IV3 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4iv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iv3 OCA], [https://pdbe.org/4iv3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4iv3 RCSB], [https://www.ebi.ac.uk/pdbsum/4iv3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4iv3 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4iv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iv3 OCA], [https://pdbe.org/4iv3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4iv3 RCSB], [https://www.ebi.ac.uk/pdbsum/4iv3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4iv3 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/Q6PN23_9PICO Q6PN23_9PICO] Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266] RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS000199_004_010047] | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Foot-and-mouth disease virus A]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Burman | [[Category: Burman A]] | ||
[[Category: Charleston | [[Category: Charleston B]] | ||
[[Category: Fry | [[Category: Fry EE]] | ||
[[Category: Jackson | [[Category: Jackson T]] | ||
[[Category: Jones | [[Category: Jones IM]] | ||
[[Category: Kotecha | [[Category: Kotecha A]] | ||
[[Category: Loureiro | [[Category: Loureiro S]] | ||
[[Category: Porta | [[Category: Porta C]] | ||
[[Category: Ren | [[Category: Ren J]] | ||
[[Category: Stuart | [[Category: Stuart DI]] | ||