4iq8: Difference between revisions
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The | ==Crystal structure of glyceraldehyde-3-phosphate dehydrogenase 3 from Saccharomyces cerevisiae== | ||
<StructureSection load='4iq8' size='340' side='right'caption='[[4iq8]], [[Resolution|resolution]] 2.49Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4iq8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IQ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IQ8 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.49Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4iq8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iq8 OCA], [https://pdbe.org/4iq8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4iq8 RCSB], [https://www.ebi.ac.uk/pdbsum/4iq8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4iq8 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/G3P3_YEAST G3P3_YEAST] | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is an important enzyme in the glycolytic pathway. In addition to its conventional metabolic role, GAPDH has been identified to possess diverse cellular functions. In this study, glyceraldehyde-3-phosphate dehydrogenase 3, the third isoform of GAPDH from Saccharomyces cerevisiae, was cloned, expressed, purified and crystallized. The crystals belonged to space group I4(1)22, with unit-cell parameters a = b = 116.13, c = 119.21 A. X-ray diffraction data were collected to a resolution of 2.6 A. The structure was solved by molecular replacement and refinement is in progress. | |||
Preliminary crystallographic analysis of glyceraldehyde-3-phosphate dehydrogenase 3 from Saccharomyces cerevisiae.,Liu Q, Wang H, Liu H, Teng M, Li X Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Aug;68(Pt 8):978-80. doi: , 10.1107/S1744309112028989. Epub 2012 Jul 31. PMID:22869137<ref>PMID:22869137</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
<div class="pdbe-citations 4iq8" style="background-color:#fffaf0;"></div> | |||
==See Also== | |||
*[[Glyceraldehyde-3-phosphate dehydrogenase 3D structures|Glyceraldehyde-3-phosphate dehydrogenase 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae S288C]] | |||
[[Category: Li X]] | |||
[[Category: Liu Q]] | |||
[[Category: Niu L]] | |||
[[Category: Teng M]] | |||
[[Category: Wang H]] |