4ilj: Difference between revisions
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==Crystal structure of an Prp8p RNaseH W1911A mutant protein== | ==Crystal structure of an Prp8p RNaseH W1911A mutant protein== | ||
<StructureSection load='4ilj' size='340' side='right' caption='[[4ilj]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='4ilj' size='340' side='right'caption='[[4ilj]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4ilj]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4ilj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ILJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ILJ FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.0001Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ilj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ilj OCA], [https://pdbe.org/4ilj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ilj RCSB], [https://www.ebi.ac.uk/pdbsum/4ilj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ilj ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/PRP8_YEAST PRP8_YEAST] Required for pre-spliceosome formation, which is the first step of pre-mRNA splicing. This protein is associated with snRNP U5. Has a role in branch site-3' splice site selection. Associates with the branch site-3' splice 3'-exon region. Also has a role in cell cycle.<ref>PMID:2835658</ref> <ref>PMID:9150140</ref> <ref>PMID:12773561</ref> <ref>PMID:18779563</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
*[[Pre-mRNA | *[[Pre-mRNA splicing factors 3D structures|Pre-mRNA splicing factors 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Saccharomyces cerevisiae S288C]] | ||
[[Category: | [[Category: Heroven C]] | ||
[[Category: Santos KF]] | |||
[[Category: | [[Category: Wahl MC]] | ||
[[Category: | [[Category: Weber G]] | ||
[[Category: | |||