4il4: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
 ==The pentameric ligand-gated ion channel GLIC in complex with Se-DDM==
-<StructureSection load='4il4' size='340' side='right' caption='[[4il4]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
+<StructureSection load='4il4' size='340' side='right'caption='[[4il4]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4il4]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Glovi Glovi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IL4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IL4 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4il4]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Gloeobacter_violaceus_PCC_7421 Gloeobacter violaceus PCC 7421]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IL4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IL4 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LSM:DODECYL+4-O-ALPHA-D-GLUCOPYRANOSYL-1-SELENO-BETA-D-GLUCOPYRANOSIDE'>LSM</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4hfi|4hfi]], [[4il9|4il9]], [[4ila|4ila]], [[4ilb|4ilb]], [[4ilc|4ilc]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LSM:DODECYL+4-O-ALPHA-D-GLUCOPYRANOSYL-1-SELENO-BETA-D-GLUCOPYRANOSIDE'>LSM</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">glvI, glr4197 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=251221 GLOVI])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4il4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4il4 OCA], [https://pdbe.org/4il4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4il4 RCSB], [https://www.ebi.ac.uk/pdbsum/4il4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4il4 ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4il4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4il4 OCA], [http://pdbe.org/4il4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4il4 RCSB], [http://www.ebi.ac.uk/pdbsum/4il4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4il4 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI]] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>
+[https://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 22: / Line 21: @@
 ==See Also==
-*[[Ion channels|Ion channels]]
+*[[Ion channels 3D structures|Ion channels 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Glovi]]
+[[Category: Gloeobacter violaceus PCC 7421]]
-[[Category: Corringer, P J]]
+[[Category: Large Structures]]
-[[Category: Delarue, M]]
+[[Category: Corringer PJ]]
-[[Category: Malherbe, L]]
+[[Category: Delarue M]]
-[[Category: Sauguet, L]]
+[[Category: Malherbe L]]
-[[Category: Ion channel]]
+[[Category: Sauguet L]]
-[[Category: Membrane]]
-[[Category: Membrane protein]]
-[[Category: Pentameric ligand-gated ion channel]]
-[[Category: Transport protein]]