4h3y: Difference between revisions

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==Crystal structure of an asymmetric dimer of a tRNA (guanine-(N(1)-)-methyltransferase from Burkholderia phymatum bound to S-adenosyl homocystein in one half-site==
==Crystal structure of an asymmetric dimer of a tRNA (guanine-(N(1)-)-methyltransferase from Burkholderia phymatum bound to S-adenosyl homocystein in one half-site==
<StructureSection load='4h3y' size='340' side='right' caption='[[4h3y]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='4h3y' size='340' side='right'caption='[[4h3y]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4h3y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Burkholderia_phymatum_stm815 Burkholderia phymatum stm815]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H3Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4H3Y FirstGlance]. <br>
<table><tr><td colspan='2'>[[4h3y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Paraburkholderia_phymatum_STM815 Paraburkholderia phymatum STM815]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H3Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H3Y FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4h3z|4h3z]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Bphy_0771, trmD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=391038 Burkholderia phymatum STM815])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h3y OCA], [https://pdbe.org/4h3y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h3y RCSB], [https://www.ebi.ac.uk/pdbsum/4h3y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h3y ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine(37)-N(1))-methyltransferase tRNA (guanine(37)-N(1))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.228 2.1.1.228] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h3y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4h3y RCSB], [http://www.ebi.ac.uk/pdbsum/4h3y PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TRMD_PARP8 TRMD_PARP8] Specifically methylates guanosine-37 in various tRNAs.[HAMAP-Rule:MF_00605]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4h3y" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[TRNA methyltransferase|TRNA methyltransferase]]
*[[TRNA methyltransferase 3D structures|TRNA methyltransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Burkholderia phymatum stm815]]
[[Category: Large Structures]]
[[Category: Structural genomic]]
[[Category: Paraburkholderia phymatum STM815]]
[[Category: Domain swapped homodimer]]
[[Category: Food pathogen]]
[[Category: G37 methyltransferase]]
[[Category: M1g-methyltransferase]]
[[Category: National institute of allergy and infectious disease]]
[[Category: Niaid]]
[[Category: Nitrogen fixation]]
[[Category: Proteobacteria]]
[[Category: S-adenosyl-homocysteine]]
[[Category: S-adenosyl-methionine]]
[[Category: Sah]]
[[Category: Sam]]
[[Category: Ssgcid]]
[[Category: Transferase]]
[[Category: Trmd]]
[[Category: Trna modification]]

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