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==Crystal Structure of the K182R, A183P mutant manganese superoxide dismutase from Sacchromyces cerevisiae== | ==Crystal Structure of the K182R, A183P mutant manganese superoxide dismutase from Sacchromyces cerevisiae== | ||
<StructureSection load='4f6e' size='340' side='right' caption='[[4f6e]], [[Resolution|resolution]] 1.60Å' scene=''> | <StructureSection load='4f6e' size='340' side='right'caption='[[4f6e]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4f6e]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4f6e]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F6E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F6E FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f6e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f6e OCA], [https://pdbe.org/4f6e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f6e RCSB], [https://www.ebi.ac.uk/pdbsum/4f6e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f6e ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/SODM_YEAST SODM_YEAST] Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. | ||
==See Also== | ==See Also== | ||
*[[Superoxide | *[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Saccharomyces cerevisiae S288C]] | ||
[[Category: Cascio | [[Category: Cascio D]] | ||
[[Category: Sheng | [[Category: Sheng Y]] | ||
[[Category: Valentine | [[Category: Valentine JS]] | ||
Latest revision as of 17:58, 20 September 2023
Crystal Structure of the K182R, A183P mutant manganese superoxide dismutase from Sacchromyces cerevisiaeCrystal Structure of the K182R, A183P mutant manganese superoxide dismutase from Sacchromyces cerevisiae
Structural highlights
FunctionSODM_YEAST Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. See Also |
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