2b4k: Difference between revisions

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==Acetobacter turbidans alpha-amino acid ester hydrolase complexed with phenylglycine==
==Acetobacter turbidans alpha-amino acid ester hydrolase complexed with phenylglycine==
<StructureSection load='2b4k' size='340' side='right' caption='[[2b4k]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
<StructureSection load='2b4k' size='340' side='right'caption='[[2b4k]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2b4k]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"acetobacter_acidum-mucosum"_(sic)_tosic_and_walker_1950 "acetobacter acidum-mucosum" (sic) tosic and walker 1950]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B4K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B4K FirstGlance]. <br>
<table><tr><td colspan='2'>[[2b4k]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Acetobacter_pasteurianus Acetobacter pasteurianus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B4K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B4K FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG9:D-PHENYLGLYCINE'>PG9</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aehA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=438 "Acetobacter acidum-mucosum" (sic) Tosic and Walker 1950])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG9:D-PHENYLGLYCINE'>PG9</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alpha-amino-acid_esterase Alpha-amino-acid esterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.43 3.1.1.43] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b4k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b4k OCA], [https://pdbe.org/2b4k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b4k RCSB], [https://www.ebi.ac.uk/pdbsum/2b4k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b4k ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b4k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b4k OCA], [http://pdbe.org/2b4k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2b4k RCSB], [http://www.ebi.ac.uk/pdbsum/2b4k PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8VRK8_ACEPA Q8VRK8_ACEPA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b4/2b4k_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b4/2b4k_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b4k ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Alpha-amino-acid esterase]]
[[Category: Acetobacter pasteurianus]]
[[Category: Barends, T R.M]]
[[Category: Large Structures]]
[[Category: Dijkstra, B W]]
[[Category: Barends TRM]]
[[Category: Janssen, D B]]
[[Category: Dijkstra BW]]
[[Category: Jekel, P A]]
[[Category: Janssen DB]]
[[Category: Polderman-Tijmes, J J]]
[[Category: Jekel PA]]
[[Category: Williams, C]]
[[Category: Polderman-Tijmes JJ]]
[[Category: Wybenga, G]]
[[Category: Williams C]]
[[Category: Alpha-beta hydrolase]]
[[Category: Wybenga G]]
[[Category: Hydrolase]]

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