1vpk: Difference between revisions

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-[[Image:1vpk.png|left|200px]]
-{{STRUCTURE_1vpk|  PDB=1vpk  |  SCENE=  }}
+==Crystal structure of DNA polymerase III, beta subunit (TM0262) from Thermotoga maritima at 2.00 A resolution==
+<StructureSection load='1vpk' size='340' side='right'caption='[[1vpk]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-===Crystal structure of DNA polymerase III, beta subunit (TM0262) from Thermotoga maritima at 2.00 A resolution===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1vpk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VPK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VPK FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vpk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vpk OCA], [https://pdbe.org/1vpk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vpk RCSB], [https://www.ebi.ac.uk/pdbsum/1vpk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vpk ProSAT], [https://www.topsan.org/Proteins/JCSG/1vpk TOPSAN]</span></td></tr>
-[[1vpk]] is a 1 chain structure of [[DNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VPK OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q9WYA0_THEMA Q9WYA0_THEMA] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA (By similarity).[PIRNR:PIRNR000804]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vp/1vpk_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vpk ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[DNA polymerase|DNA polymerase]]
+*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
-[[Category: DNA-directed DNA polymerase]]
+__TOC__
-[[Category: Thermotoga maritima]]
+</StructureSection>
-[[Category: JCSG, Joint Center for Structural Genomics.]]
+[[Category: Large Structures]]
-[[Category: Beta subunit]]
+[[Category: Thermotoga maritima MSB8]]
-[[Category: Dna polymerase iii]]
-[[Category: Jcsg]]
-[[Category: Joint center for structural genomic]]
-[[Category: Protein structure initiative]]
-[[Category: Psi]]
-[[Category: Structural genomic]]
-[[Category: Tm0262]]
-[[Category: Transferase]]