1mpu: Difference between revisions
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==Crystal Structure of the free human NKG2D immunoreceptor== | ==Crystal Structure of the free human NKG2D immunoreceptor== | ||
<StructureSection load='1mpu' size='340' side='right' caption='[[1mpu]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='1mpu' size='340' side='right'caption='[[1mpu]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1mpu]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1mpu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MPU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MPU FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mpu OCA], [https://pdbe.org/1mpu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mpu RCSB], [https://www.ebi.ac.uk/pdbsum/1mpu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mpu ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/NKG2D_HUMAN NKG2D_HUMAN] Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</div> | </div> | ||
<div class="pdbe-citations 1mpu" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 1mpu" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[NK cell receptor|NK cell receptor]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Baker D]] | ||
[[Category: | [[Category: Kortemme T]] | ||
[[Category: | [[Category: McFarland BJ]] | ||
[[Category: | [[Category: Strong RK]] | ||