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==Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked with 2.5 mM Na+ and 1mM Ca2+==
==Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked with 2.5 mM Na+ and 1mM Ca2+==
<StructureSection load='5jdf' size='340' side='right' caption='[[5jdf]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
<StructureSection load='5jdf' size='340' side='right'caption='[[5jdf]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5jdf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Metja Metja]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JDF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JDF FirstGlance]. <br>
<table><tr><td colspan='2'>[[5jdf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii_DSM_2661 Methanocaldococcus jannaschii DSM 2661]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JDF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JDF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MYS:PENTADECANE'>MYS</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5jdq|5jdq]], [[5jdn|5jdn]], [[5jdm|5jdm]], [[5jdl|5jdl]], [[5jdh|5jdh]], [[5jdg|5jdg]], [[5hwx|5hwx]], [[5hwy|5hwy]], [[5hxc|5hxc]], [[5hxe|5hxe]], [[5hxh|5hxh]], [[5hxr|5hxr]], [[5hxs|5hxs]], [[5hya|5hya]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MYS:PENTADECANE'>MYS</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MJ0091 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243232 METJA])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jdf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jdf OCA], [https://pdbe.org/5jdf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jdf RCSB], [https://www.ebi.ac.uk/pdbsum/5jdf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jdf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jdf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jdf OCA], [http://pdbe.org/5jdf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jdf RCSB], [http://www.ebi.ac.uk/pdbsum/5jdf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jdf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Y091_METJA Y091_METJA]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Metja]]
[[Category: Large Structures]]
[[Category: Faraldo-Gomez, J D]]
[[Category: Methanocaldococcus jannaschii DSM 2661]]
[[Category: Jiang, Y X]]
[[Category: Faraldo-Gomez JD]]
[[Category: Liao, J]]
[[Category: Jiang YX]]
[[Category: Calcium signalling]]
[[Category: Liao J]]
[[Category: Induced conformational change]]
[[Category: Membrane protein]]
[[Category: Membrane transporter]]
[[Category: Na+/ca2+ exchange]]

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