3odo: Difference between revisions

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-[[Image:3odo.jpg|left|200px]]
-<!--
+==Crystal Structure of the DH/PH Domains of p115-RhoGEF==
-The line below this paragraph, containing "STRUCTURE_3odo", creates the "Structure Box" on the page.
+<StructureSection load='3odo' size='340' side='right'caption='[[3odo]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3odo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ODO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ODO FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3odo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3odo OCA], [https://pdbe.org/3odo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3odo RCSB], [https://www.ebi.ac.uk/pdbsum/3odo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3odo ProSAT]</span></td></tr>
-{{STRUCTURE_3odo|  PDB=3odo  |  SCENE=  }}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ARHG1_HUMAN ARHG1_HUMAN] Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits. Acts as GTPase-activating protein (GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor (GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation.<ref>PMID:8810315</ref> <ref>PMID:9641915</ref> <ref>PMID:9641916</ref> <ref>PMID:20098430</ref>
-===Crystal Structure of the DH/PH Domains of p115-RhoGEF===
+==See Also==
+*[[Rho guanine nucleotide exchange factor 3D structures|Rho guanine nucleotide exchange factor 3D structures]]
+== References ==
-==About this Structure==
+<references/>
-[[3odo]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ODO OCA].
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Chen, Z.]]
+[[Category: Large Structures]]
-[[Category: Guo, L.]]
+[[Category: Chen Z]]
-[[Category: Sprang, S R.]]
+[[Category: Guo L]]
-[[Category: Sternweis, P C.]]
+[[Category: Sprang SR]]
+[[Category: Sternweis PC]]