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==Crystal structure of Staphylococcal nuclease variant Delta+PHS L125A at cryogenic temperature==
==Crystal structure of Staphylococcal nuclease variant Delta+PHS L125A at cryogenic temperature==
<StructureSection load='3nxw' size='340' side='right' caption='[[3nxw]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='3nxw' size='340' side='right'caption='[[3nxw]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3nxw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NXW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NXW FirstGlance]. <br>
<table><tr><td colspan='2'>[[3nxw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NXW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NXW FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=THP:THYMIDINE-3,5-DIPHOSPHATE'>THP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3bdc|3bdc]], [[3meh|3meh]], [[3mhb|3mhb]], [[3mxp|3mxp]], [[3mvv|3mvv]], [[3mz5|3mz5]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=THP:THYMIDINE-3,5-DIPHOSPHATE'>THP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nxw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nxw RCSB], [http://www.ebi.ac.uk/pdbsum/3nxw PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nxw OCA], [https://pdbe.org/3nxw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nxw RCSB], [https://www.ebi.ac.uk/pdbsum/3nxw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nxw ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU]] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.  
[https://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3nxw" style="background-color:#fffaf0;"></div>
==See Also==
*[[Staphylococcal nuclease 3D structures|Staphylococcal nuclease 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
[[Category: Caro, J A]]
[[Category: Caro JA]]
[[Category: Garcia-Moreno, E B]]
[[Category: Garcia-Moreno EB]]
[[Category: Heroux, A]]
[[Category: Heroux A]]
[[Category: Schlessman, J L]]
[[Category: Schlessman JL]]
[[Category: Cavity]]
[[Category: Hydrolase]]
[[Category: Hyperstable variant]]
[[Category: Pdtp]]
[[Category: Pressure]]
[[Category: Staphylococcal nuclease]]

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