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{{STRUCTURE_3nvs|  PDB=3nvs  |  SCENE=  }}
===1.02 Angstrom resolution crystal structure of 3-phosphoshikimate 1-carboxyvinyltransferase from Vibrio cholerae in complex with shikimate-3-phosphate (partially photolyzed) and glyphosate===


==About this Structure==
==1.02 Angstrom resolution crystal structure of 3-phosphoshikimate 1-carboxyvinyltransferase from Vibrio cholerae in complex with shikimate-3-phosphate (partially photolyzed) and glyphosate==
[[3nvs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NVS OCA].  
<StructureSection load='3nvs' size='340' side='right'caption='[[3nvs]], [[Resolution|resolution]] 1.02&Aring;' scene=''>
[[Category: 3-phosphoshikimate 1-carboxyvinyltransferase]]
== Structural highlights ==
<table><tr><td colspan='2'>[[3nvs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NVS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NVS FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.021&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GPJ:GLYPHOSATE'>GPJ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=S3P:SHIKIMATE-3-PHOSPHATE'>S3P</scene>, <scene name='pdbligand=SKM:(3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC+ACID'>SKM</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nvs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nvs OCA], [https://pdbe.org/3nvs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nvs RCSB], [https://www.ebi.ac.uk/pdbsum/3nvs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nvs ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AROA_VIBCH AROA_VIBCH] Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.[HAMAP-Rule:MF_00210]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nv/3nvs_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3nvs ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[EPSP synthase 3D structures|EPSP synthase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Vibrio cholerae]]
[[Category: Vibrio cholerae]]
[[Category: Anderson, W F.]]
[[Category: Anderson WF]]
[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
[[Category: Halavaty A]]
[[Category: Halavaty, A.]]
[[Category: Light SH]]
[[Category: Light, S H.]]
[[Category: Minasov G]]
[[Category: Minasov, G.]]
[[Category: Papazisi L]]
[[Category: Papazisi, L.]]
[[Category: Shuvalova G]]
[[Category: Shuvalova, G.]]
[[Category: Center for structural genomics of infectious disease]]
[[Category: Csgid]]
[[Category: Epsp synthase]]
[[Category: Inside-out alpha-beta barrel]]
[[Category: Structural genomic]]
[[Category: Transferase]]

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