3np5: Difference between revisions

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-[[Image:3np5.jpg|left|200px]]
-<!--
+==Crystal structure of an abridged form of the mature ectodomain of the human receptor-type protein tyrosine phosphatase ICA512/IA-2 AT pH 4.5==
-The line below this paragraph, containing "STRUCTURE_3np5", creates the "Structure Box" on the page.
+<StructureSection load='3np5' size='340' side='right'caption='[[3np5]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3np5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NP5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NP5 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-{{STRUCTURE_3np5|  PDB=3np5  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3np5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3np5 OCA], [https://pdbe.org/3np5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3np5 RCSB], [https://www.ebi.ac.uk/pdbsum/3np5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3np5 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PTPRN_HUMAN PTPRN_HUMAN] Implicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2.<ref>PMID:8144912</ref> <ref>PMID:8641276</ref>
-===Crystal structure of an abridged form of the mature ectodomain of the human receptor-type protein tyrosine phosphatase ICA512/IA-2 AT pH 4.5===
+==See Also==
+*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]]
+== References ==
-==About this Structure==
+<references/>
-[[3np5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NP5 OCA].
+__TOC__
+</StructureSection>
-==Reference==
-<ref group="xtra">PMID:18048354</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
-[[Category: Ermacora, M R.]]
+[[Category: Large Structures]]
-[[Category: Jakoncic, J.]]
+[[Category: Ermacora MR]]
-[[Category: Poskus, E.]]
+[[Category: Jakoncic J]]
-[[Category: Primo, M E.]]
+[[Category: Poskus E]]
+[[Category: Primo ME]]