3no9: Difference between revisions

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-[[Image:3no9.png|left|200px]]
-{{STRUCTURE_3no9|  PDB=3no9  |  SCENE=  }}
+==Crystal Structure of apo fumarate hydratase from Mycobacterium tuberculosis==
+<StructureSection load='3no9' size='340' side='right'caption='[[3no9]], [[Resolution|resolution]] 2.48&Aring;' scene=''>
-===Crystal Structure of apo fumarate hydratase from Mycobacterium tuberculosis===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3no9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NO9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NO9 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.48&#8491;</td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3no9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3no9 OCA], [https://pdbe.org/3no9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3no9 RCSB], [https://www.ebi.ac.uk/pdbsum/3no9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3no9 ProSAT]</span></td></tr>
-[[3no9]] is a 4 chain structure of [[Fumarase]] with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NO9 OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/FUMC_MYCTU FUMC_MYCTU] Catalyzes the reversible addition of water to fumarate to give L-malate.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/no/3no9_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3no9 ConSurf].
+<div style="clear:both"></div>
 ==See Also==
 *[[Fumarase|Fumarase]]
-[[Category: Fumarate hydratase]]
+__TOC__
-[[Category: Mycobacterium tuberculosis]]
+</StructureSection>
-[[Category: Hung, L W.]]
+[[Category: Large Structures]]
-[[Category: Li, H.]]
+[[Category: Mycobacterium tuberculosis H37Rv]]
-[[Category: Sacchettini, J C.]]
+[[Category: Hung L-W]]
-[[Category: Swanson, S.]]
+[[Category: Li H]]
-[[Category: TBSGC, TB Structural Genomics Consortium.]]
+[[Category: Sacchettini JC]]
-[[Category: Yu, M.]]
+[[Category: Swanson S]]
-[[Category: Apo]]
+[[Category: Yu M]]
-[[Category: Fumarate hydratase]]
-[[Category: Lyase]]
-[[Category: Lyase class i]]
-[[Category: Structural genomic]]
-[[Category: Tb structural genomics consortium]]
-[[Category: Tbsgc]]
-[[Category: Tricarboxylic acid cycle]]