3n77: Difference between revisions

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==Crystal structure of Idp01880, putative NTP pyrophosphohydrolase of Salmonella typhimurium LT2==
==Crystal structure of Idp01880, putative NTP pyrophosphohydrolase of Salmonella typhimurium LT2==
<StructureSection load='3n77' size='340' side='right' caption='[[3n77]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
<StructureSection load='3n77' size='340' side='right'caption='[[3n77]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3n77]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N77 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3N77 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3n77]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N77 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N77 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nudI, STM2295, yfaO ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 Salmonella enterica subsp. enterica serovar Typhimurium])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n77 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3n77 RCSB], [http://www.ebi.ac.uk/pdbsum/3n77 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n77 OCA], [https://pdbe.org/3n77 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n77 RCSB], [https://www.ebi.ac.uk/pdbsum/3n77 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n77 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NUDI_SALTY NUDI_SALTY] Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP) (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n7/3n77_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n7/3n77_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3n77 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
*[[Nucleoside triphosphatase|Nucleoside triphosphatase]]
*[[Sandbox 30008|Sandbox 30008]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
[[Category: Large Structures]]
[[Category: Anderson, W F]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
[[Category: Structural genomic]]
[[Category: Anderson WF]]
[[Category: Cooper, D R]]
[[Category: Cooper DR]]
[[Category: Derewenda, U]]
[[Category: Derewenda U]]
[[Category: Derewenda, Z S]]
[[Category: Derewenda ZS]]
[[Category: Frydrysiak, J]]
[[Category: Frydrysiak J]]
[[Category: ISFI, Integrated Center for Structure and Function Innovation]]
[[Category: Hydrolase]]
[[Category: Integrated center for structure and function innovation]]
[[Category: Isfi]]
[[Category: PSI, Protein structure initiative]]
[[Category: Surface entropy reduction]]

Latest revision as of 12:09, 6 September 2023

Crystal structure of Idp01880, putative NTP pyrophosphohydrolase of Salmonella typhimurium LT2Crystal structure of Idp01880, putative NTP pyrophosphohydrolase of Salmonella typhimurium LT2

Structural highlights

3n77 is a 2 chain structure with sequence from Salmonella enterica subsp. enterica serovar Typhimurium. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.86Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NUDI_SALTY Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP) (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3n77, resolution 1.86Å

Drag the structure with the mouse to rotate

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