3n64: Difference between revisions

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 ==Structure of neuronal nitric oxide synthase D597N mutant heme domain in complex with 6,6'-(2,2'-(5-amino-1,3-phenylene)bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine)==
-<StructureSection load='3n64' size='340' side='right' caption='[[3n64]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
+<StructureSection load='3n64' size='340' side='right'caption='[[3n64]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3n64]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N64 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3N64 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3n64]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N64 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N64 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=XFN:6,6-[(5-AMINOBENZENE-1,3-DIYL)DIETHANE-2,1-DIYL]BIS(4-METHYLPYRIDIN-2-AMINE)'>XFN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3n5p|3n5p]], [[3n5q|3n5q]], [[3n5r|3n5r]], [[3n5s|3n5s]], [[3n5t|3n5t]], [[3n5v|3n5v]], [[3n5w|3n5w]], [[3n5x|3n5x]], [[3n5y|3n5y]], [[3n5z|3n5z]], [[3n60|3n60]], [[3n61|3n61]], [[3n62|3n62]], [[3n63|3n63]], [[3n65|3n65]], [[3n66|3n66]], [[3n67|3n67]], [[3n68|3n68]], [[3n69|3n69]], [[3n6a|3n6a]], [[3n6b|3n6b]], [[3n6c|3n6c]], [[3n6d|3n6d]], [[3n6e|3n6e]], [[3n6f|3n6f]], [[3n6g|3n6g]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=XFN:6,6-[(5-AMINOBENZENE-1,3-DIYL)DIETHANE-2,1-DIYL]BIS(4-METHYLPYRIDIN-2-AMINE)'>XFN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NOS3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n64 OCA], [https://pdbe.org/3n64 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n64 RCSB], [https://www.ebi.ac.uk/pdbsum/3n64 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n64 ProSAT]</span></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitric-oxide_synthase_(NADPH_dependent) Nitric-oxide synthase (NADPH dependent)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.39 1.14.13.39] </span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n64 OCA], [http://pdbe.org/3n64 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3n64 RCSB], [http://www.ebi.ac.uk/pdbsum/3n64 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3n64 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/NOS1_RAT NOS1_RAT]] Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum.
+[https://www.uniprot.org/uniprot/NOS1_RAT NOS1_RAT] Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum.
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 23: / Line 21: @@
 ==See Also==
-*[[Nitric Oxide Synthase|Nitric Oxide Synthase]]
+*[[Nitric Oxide Synthase 3D structures|Nitric Oxide Synthase 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Buffalo rat]]
+[[Category: Large Structures]]
-[[Category: Delker, S L]]
+[[Category: Rattus norvegicus]]
-[[Category: Li, H]]
+[[Category: Delker SL]]
-[[Category: Poulos, T L]]
+[[Category: Li H]]
-[[Category: Heme enzyme]]
+[[Category: Poulos TL]]
-[[Category: Nitric oxide synthase]]
-[[Category: Oxidoreductase]]
-[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
-[[Category: Substrate inhibitor]]
-[[Category: Zn bindings']]