3n5e: Difference between revisions
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==Crystal Structure of human thymidylate synthase bound to a peptide inhibitor== | ==Crystal Structure of human thymidylate synthase bound to a peptide inhibitor== | ||
<StructureSection load='3n5e' size='340' side='right' caption='[[3n5e]], [[Resolution|resolution]] 2.26Å' scene=''> | <StructureSection load='3n5e' size='340' side='right'caption='[[3n5e]], [[Resolution|resolution]] 2.26Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3n5e]] is a 3 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3n5e]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N5E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N5E FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.26Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SCH:S-METHYL-THIO-CYSTEINE'>SCH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n5e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n5e OCA], [https://pdbe.org/3n5e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n5e RCSB], [https://www.ebi.ac.uk/pdbsum/3n5e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n5e ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/TYSY_HUMAN TYSY_HUMAN] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.<ref>PMID:21876188</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 3n5e" style="background-color:#fffaf0;"></div> | |||
==See Also== | ==See Also== | ||
*[[Thymidylate synthase|Thymidylate synthase]] | *[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Cardinale | [[Category: Cardinale D]] | ||
[[Category: Costi | [[Category: Costi MP]] | ||
[[Category: Ferrari | [[Category: Ferrari S]] | ||
[[Category: Guaitoli | [[Category: Guaitoli G]] | ||
[[Category: Luciani | [[Category: Luciani R]] | ||
[[Category: Mangani | [[Category: Mangani S]] | ||
[[Category: Myllykallio | [[Category: Myllykallio H]] | ||
[[Category: Pozzi | [[Category: Pozzi C]] | ||
[[Category: Tondi | [[Category: Tondi D]] | ||