3n2l: Difference between revisions

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{{STRUCTURE_3n2l|  PDB=3n2l  |  SCENE=  }}
===2.1 Angstrom resolution crystal structure of an Orotate Phosphoribosyltransferase (pyrE) from Vibrio cholerae O1 biovar eltor str. N16961===


==Function==
==2.1 Angstrom resolution crystal structure of an Orotate Phosphoribosyltransferase (pyrE) from Vibrio cholerae O1 biovar eltor str. N16961==
[[http://www.uniprot.org/uniprot/PYRE_VIBCH PYRE_VIBCH]] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity).  
<StructureSection load='3n2l' size='340' side='right'caption='[[3n2l]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[3n2l]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N2L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N2L FirstGlance]. <br>
[[3n2l]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N2L OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n2l OCA], [https://pdbe.org/3n2l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n2l RCSB], [https://www.ebi.ac.uk/pdbsum/3n2l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n2l ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PYRE_VIBCH PYRE_VIBCH] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n2/3n2l_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3n2l ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Phosphoribosyltransferase|Phosphoribosyltransferase]]
*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
[[Category: Orotate phosphoribosyltransferase]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Vibrio cholerae]]
[[Category: Vibrio cholerae]]
[[Category: Anderson, W F.]]
[[Category: Anderson WF]]
[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
[[Category: Dubrovska I]]
[[Category: Dubrovska, I.]]
[[Category: Halavaty AS]]
[[Category: Halavaty, A S.]]
[[Category: Kwon K]]
[[Category: Kwon, K.]]
[[Category: Minasov G]]
[[Category: Minasov, G.]]
[[Category: Shuvalova L]]
[[Category: Shuvalova, L.]]
[[Category: Winsor J]]
[[Category: Winsor, J.]]
[[Category: Center for structural genomics of infectious disease]]
[[Category: Csgid]]
[[Category: Glycosyltransferase]]
[[Category: Infectious disease]]
[[Category: Magnesium]]
[[Category: Orotate phosphoribosyltransferase]]
[[Category: Pyrimidine biosynthesis]]
[[Category: Pyrimidine ribonucleotide biosynthesis]]
[[Category: Transferase]]

Latest revision as of 12:07, 6 September 2023

2.1 Angstrom resolution crystal structure of an Orotate Phosphoribosyltransferase (pyrE) from Vibrio cholerae O1 biovar eltor str. N169612.1 Angstrom resolution crystal structure of an Orotate Phosphoribosyltransferase (pyrE) from Vibrio cholerae O1 biovar eltor str. N16961

Structural highlights

3n2l is a 8 chain structure with sequence from Vibrio cholerae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.1Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PYRE_VIBCH Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3n2l, resolution 2.10Å

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