3mj3: Difference between revisions

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-{{Seed}}
-[[Image:3mj3.png|left|200px]]
-<!--
+==Cricket Paralysis Virus IGR IRES Domain 3 RNA bound to selenate==
-The line below this paragraph, containing "STRUCTURE_3mj3", creates the "Structure Box" on the page.
+<StructureSection load='3mj3' size='340' side='right'caption='[[3mj3]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3mj3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MJ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MJ3 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SE4:SELENATE+ION'>SE4</scene></td></tr>
-{{STRUCTURE_3mj3|  PDB=3mj3  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mj3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mj3 OCA], [https://pdbe.org/3mj3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mj3 RCSB], [https://www.ebi.ac.uk/pdbsum/3mj3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mj3 ProSAT]</span></td></tr>
+</table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Although RNA molecules are highly negatively charged, anions have been observed bound to RNA in crystal structures. It has been proposed that anion binding sites found within isolated RNAs represent regions of the molecule that could be involved in intermolecular interactions, indicating potential contact points for negatively charged amino acids from proteins or phosphate groups from an RNA. Several types of anion binding sites have been cataloged based on available structures. However, currently there is no method for unambiguously assigning anions to crystallographic electron density, and this has precluded more detailed analysis of RNA-anion interaction motifs and their significance. We therefore soaked selenate into two different types of RNA crystals and used the anomalous signal from these anions to identify binding sites in these RNA molecules unambiguously. Examination of these sites and comparison with other suspected anion binding sites reveals features of anion binding motifs, and shows that selenate may be a useful tool for studying RNA-anion interactions.
-===Cricket Paralysis Virus IGR IRES Domain 3 RNA bound to selenate===
+Identification and characterization of anion binding sites in RNA.,Kieft JS, Chase E, Costantino DA, Golden BL RNA. 2010 Jun;16(6):1118-23. Epub 2010 Apr 21. PMID:20410239<ref>PMID:20410239</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-<!--
+</div>
-The line below this paragraph, {{ABSTRACT_PUBMED_20410239}}, adds the Publication Abstract to the page
+<div class="pdbe-citations 3mj3" style="background-color:#fffaf0;"></div>
-(as it appears on PubMed at http://www.pubmed.gov), where 20410239 is the PubMed ID number.
+== References ==
--->
+<references/>
-{{ABSTRACT_PUBMED_20410239}}
+__TOC__
+</StructureSection>
-==About this Structure==
+[[Category: Large Structures]]
-MJ3 is a 2 chains structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MJ3 OCA].
+[[Category: Chase E]]
+[[Category: Costantino DA]]
-==Reference==
+[[Category: Golden BL]]
-<ref group="xtra">PMID:20410239</ref><references group="xtra"/>
+[[Category: Kieft JS]]
-[[Category: Chase, E.]]
-[[Category: Costantino, D A.]]
-[[Category: Golden, B L.]]
-[[Category: Kieft, J S.]]
-[[Category: Anion]]
-[[Category: Rna]]
-[[Category: Rna pseudoknot]]
-[[Category: Selenate]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 10 10:50:09 2010''