3mew: Difference between revisions

<StructureSection load='3mew' size='340' side='right'caption='[[3mew]], [[Resolution|resolution]] 1.92&Aring;' scene=''>

<table><tr><td colspan='2'>[[3mew]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MEW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MEW FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.92&#8491;</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mew FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mew OCA], [https://pdbe.org/3mew PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mew RCSB], [https://www.ebi.ac.uk/pdbsum/3mew PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mew ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/SGF29_HUMAN SGF29_HUMAN] Involved in transcriptional regulation, through association with histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes. Specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3). In the SAGA-type complexes, required to recruit complexes to H3K4me. May be involved in MYC-mediated oncogenic transformation.<ref>PMID:19103755</ref>  

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Arrowsmith CH]]

[[Category: Bian CB]]

[[Category: Bochkarev A]]

[[Category: Bountra C]]

[[Category: Edwards AM]]

[[Category: Lam R]]

[[Category: Min J]]

[[Category: Weigelt J]]

[[Category: Xu C]]