3lm0: Difference between revisions

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-{{STRUCTURE_3lm0|  PDB=3lm0  |  SCENE=  }}
-===Crystal Structure of human Serine/Threonine Kinase 17B (STK17B)===
-==Function==
+==Crystal Structure of human Serine/Threonine Kinase 17B (STK17B)==
-[[http://www.uniprot.org/uniprot/ST17B_HUMAN ST17B_HUMAN]] Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis.<ref>PMID:9786912</ref>
+<StructureSection load='3lm0' size='340' side='right'caption='[[3lm0]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3lm0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LM0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LM0 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EBD:[4-({4-[(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO]-5-METHYLPYRIMIDIN-2-YL}AMINO)PHENYL]ACETONITRILE'>EBD</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lm0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lm0 OCA], [https://pdbe.org/3lm0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lm0 RCSB], [https://www.ebi.ac.uk/pdbsum/3lm0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lm0 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ST17B_HUMAN ST17B_HUMAN] Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis.<ref>PMID:9786912</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lm/3lm0_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lm0 ConSurf].
+<div style="clear:both"></div>
-==About this Structure==
+==See Also==
-[[3lm0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LM0 OCA].
+*[[Serine/threonine protein kinase 3D structures|Serine/threonine protein kinase 3D structures]]
+== References ==
-==Reference==
+<references/>
-<references group="xtra"/><references/>
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Non-specific serine/threonine protein kinase]]
+[[Category: Large Structures]]
-[[Category: Arrowsmith, C H.]]
+[[Category: Arrowsmith CH]]
-[[Category: Bountra, C.]]
+[[Category: Bountra C]]
-[[Category: Chaikuad, A.]]
+[[Category: Chaikuad A]]
-[[Category: Delft, F von.]]
+[[Category: Edwards A]]
-[[Category: Edwards, A.]]
+[[Category: Fedorov O]]
-[[Category: Fedorov, O.]]
+[[Category: Filippakopoulos P]]
-[[Category: Filippakopoulos, P.]]
+[[Category: Hapka E]]
-[[Category: Hapka, E.]]
+[[Category: Knapp S]]
-[[Category: Knapp, S.]]
+[[Category: Phillips C]]
-[[Category: Phillips, C.]]
+[[Category: Pike ACW]]
-[[Category: Pike, A C.W.]]
+[[Category: Rellos P]]
-[[Category: Rellos, P.]]
+[[Category: Soundararajan M]]
-[[Category: SGC, Structural Genomics Consortium.]]
+[[Category: Ugochukwu E]]
-[[Category: Soundararajan, M.]]
+[[Category: Wang J]]
-[[Category: Ugochukwu, E.]]
+[[Category: Weigelt J]]
-[[Category: Wang, J.]]
+[[Category: Von Delft F]]
-[[Category: Weigelt, J.]]
-[[Category: Apoptosis]]
-[[Category: Atp-binding]]
-[[Category: Dap kinase related apoptosis-inducing protein kinase 2]]
-[[Category: Death-associated protein kinase-related 2]]
-[[Category: Drak2]]
-[[Category: Kinase]]
-[[Category: Nucleotide-binding]]
-[[Category: Nucleus]]
-[[Category: Phosphoprotein]]
-[[Category: Serine/threonine kinase 17b]]
-[[Category: Serine/threonine-protein kinase]]
-[[Category: Sgc]]
-[[Category: Stk17b]]
-[[Category: Structural genomic]]
-[[Category: Structural genomics consortium]]
-[[Category: Transferase]]