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==Crystal structure of the double mutant F178Y/R181E of E.coli transaldolase B==
==Crystal structure of the double mutant F178Y/R181E of E.coli transaldolase B==
<StructureSection load='3kof' size='340' side='right' caption='[[3kof]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3kof' size='340' side='right'caption='[[3kof]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3kof]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KOF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KOF FirstGlance]. <br>
<table><tr><td colspan='2'>[[3kof]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KOF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KOF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3cwn|3cwn]], [[1onr|1onr]], [[1i2n|1i2n]], [[1i2o|1i2o]], [[1i2p|1i2p]], [[1ucw|1ucw]], [[1i2r|1i2r]], [[1i2q|1i2q]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">talB, yaaK, b0008, JW0007 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kof OCA], [https://pdbe.org/3kof PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kof RCSB], [https://www.ebi.ac.uk/pdbsum/3kof PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kof ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transaldolase Transaldolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.2.1.2 2.2.1.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kof OCA], [http://pdbe.org/3kof PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3kof RCSB], [http://www.ebi.ac.uk/pdbsum/3kof PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3kof ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TALB_ECOLI TALB_ECOLI]] Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.[HAMAP-Rule:MF_00492]  
[https://www.uniprot.org/uniprot/TALB_ECOLI TALB_ECOLI] Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.[HAMAP-Rule:MF_00492]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Transaldolase|Transaldolase]]
*[[Transaldolase 3D structures|Transaldolase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Transaldolase]]
[[Category: Large Structures]]
[[Category: Clapes, P]]
[[Category: Clapes P]]
[[Category: Gutierrez, M]]
[[Category: Gutierrez M]]
[[Category: Samland, A K]]
[[Category: Samland AK]]
[[Category: Sandalova, T]]
[[Category: Sandalova T]]
[[Category: Schneider, G]]
[[Category: Schneider G]]
[[Category: Schneider, S]]
[[Category: Schneider S]]
[[Category: Sprenger, G A]]
[[Category: Sprenger GA]]
[[Category: Aldolase]]
[[Category: Cytoplasm]]
[[Category: Directed evolution]]
[[Category: Pentose shunt]]
[[Category: Transferase]]

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