3ka9: Difference between revisions

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==Frog M-ferritin, EEH mutant, with cobalt==
==Frog M-ferritin, EEH mutant, with cobalt==
<StructureSection load='3ka9' size='340' side='right' caption='[[3ka9]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
<StructureSection load='3ka9' size='340' side='right'caption='[[3ka9]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3ka9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/American_bullfrog American bullfrog]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KA9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KA9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3ka9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lithobates_catesbeianus Lithobates catesbeianus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KA9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KA9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ka3|3ka3]], [[3ka4|3ka4]], [[3ka6|3ka6]], [[3ka8|3ka8]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ka9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ka9 OCA], [https://pdbe.org/3ka9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ka9 RCSB], [https://www.ebi.ac.uk/pdbsum/3ka9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ka9 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ka9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ka9 OCA], [http://pdbe.org/3ka9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ka9 RCSB], [http://www.ebi.ac.uk/pdbsum/3ka9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ka9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FRI2_LITCT FRI2_LITCT]] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.  
[https://www.uniprot.org/uniprot/FRI2_LITCT FRI2_LITCT] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ka/3ka9_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ka/3ka9_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
*[[Ferritin|Ferritin]]
*[[Ferritin 3D structures|Ferritin 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: American bullfrog]]
[[Category: Large Structures]]
[[Category: Ferroxidase]]
[[Category: Lithobates catesbeianus]]
[[Category: Alber, T]]
[[Category: Alber T]]
[[Category: Bhattasali, O]]
[[Category: Bhattasali O]]
[[Category: Ng, H L]]
[[Category: Ng HL]]
[[Category: Theil, E]]
[[Category: Theil E]]
[[Category: Tosha, T]]
[[Category: Tosha T]]
[[Category: Diiron]]
[[Category: Iron]]
[[Category: Iron storage]]
[[Category: Metal-binding]]
[[Category: Oxidoreductase]]

Latest revision as of 11:12, 6 September 2023

Frog M-ferritin, EEH mutant, with cobaltFrog M-ferritin, EEH mutant, with cobalt

Structural highlights

3ka9 is a 1 chain structure with sequence from Lithobates catesbeianus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.45Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

FRI2_LITCT Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3ka9, resolution 1.45Å

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OCA