3jtk: Difference between revisions

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-[[Image:3jtk.png|left|200px]]
-<!--
+==Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD90055==
-The line below this paragraph, containing "STRUCTURE_3jtk", creates the "Structure Box" on the page.
+<StructureSection load='3jtk' size='340' side='right'caption='[[3jtk]], [[Resolution|resolution]] 1.61&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3jtk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JTK FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.61&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MYA:TETRADECANOYL-COA'>MYA</scene>, <scene name='pdbligand=X55:(2R)-3-BENZYL-2-(2-BROMO-4-HYDROXY-5-METHOXYPHENYL)-1,3-THIAZOLIDIN-4-ONE'>X55</scene></td></tr>
-{{STRUCTURE_3jtk|  PDB=3jtk  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jtk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jtk OCA], [https://pdbe.org/3jtk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jtk RCSB], [https://www.ebi.ac.uk/pdbsum/3jtk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jtk ProSAT]</span></td></tr>
+</table>
-===Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD90055===
+== Function ==
+[https://www.uniprot.org/uniprot/NMT1_HUMAN NMT1_HUMAN] Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins.
+== Evolutionary Conservation ==
-==About this Structure==
+[[Image:Consurf_key_small.gif|200px|right]]
-[[3jtk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTK OCA].
+Check<jmol>
-[[Category: Glycylpeptide N-tetradecanoyltransferase]]
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jt/3jtk_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3jtk ConSurf].
+<div style="clear:both"></div>
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Arrowsmith, C H.]]
+[[Category: Large Structures]]
-[[Category: Bochkarev, A.]]
+[[Category: Arrowsmith CH]]
-[[Category: Bountra, C.]]
+[[Category: Bochkarev A]]
-[[Category: Brand, S Y.]]
+[[Category: Bountra C]]
-[[Category: Cossar, D.]]
+[[Category: Brand SY]]
-[[Category: Edwards, A M.]]
+[[Category: Cossar D]]
-[[Category: Ferguson, M A.J.]]
+[[Category: Edwards AM]]
-[[Category: Frearson, J A.]]
+[[Category: Ferguson MAJ]]
-[[Category: Hui, R.]]
+[[Category: Frearson JA]]
-[[Category: Hutchinson, A.]]
+[[Category: Hui R]]
-[[Category: Kania, A.]]
+[[Category: Hutchinson A]]
-[[Category: Kozieradzki, I.]]
+[[Category: Kania A]]
-[[Category: Lin, Y H.]]
+[[Category: Kozieradzki I]]
-[[Category: Qiu, W.]]
+[[Category: Lin Y-H]]
-[[Category: Ravichandran, M.]]
+[[Category: Qiu W]]
-[[Category: Robinson, D A.]]
+[[Category: Ravichandran M]]
-[[Category: SGC, Structural Genomics Consortium.]]
+[[Category: Robinson DA]]
-[[Category: Schapira, M.]]
+[[Category: Schapira M]]
-[[Category: Weigelt, J.]]
+[[Category: Weigelt J]]
-[[Category: Wernimont, A.]]
+[[Category: Wernimont A]]
-[[Category: Wyatt, P G.]]
+[[Category: Wyatt PG]]
-[[Category: Acyltransferase]]
-[[Category: N-myristoyltransferase]]
-[[Category: Nmt1]]
-[[Category: Phosphoprotein]]
-[[Category: Sgc]]
-[[Category: Structural genomic]]
-[[Category: Structural genomics consortium]]
-[[Category: Transferase]]