3iu1: Difference between revisions
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New page: '''Unreleased structure''' The entry 3iu1 is ON HOLD Authors: Qiu, W., Hutchinson, A., Wernimont, A., Lin, Y.-H., Kania, A., Ravichandran, M., Kozieradzki, I., Cossar, D., Schapira, M.,... |
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==Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA== | |||
<StructureSection load='3iu1' size='340' side='right'caption='[[3iu1]], [[Resolution|resolution]] 1.42Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3iu1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IU1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IU1 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.42Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MYA:TETRADECANOYL-COA'>MYA</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iu1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iu1 OCA], [https://pdbe.org/3iu1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iu1 RCSB], [https://www.ebi.ac.uk/pdbsum/3iu1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iu1 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/NMT1_HUMAN NMT1_HUMAN] Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iu/3iu1_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3iu1 ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Arrowsmith CH]] | |||
[[Category: Bochkarev A]] | |||
[[Category: Bountra C]] | |||
[[Category: Brand SY]] | |||
[[Category: Cossar D]] | |||
[[Category: Edwards AM]] | |||
[[Category: Ferguson MAJ]] | |||
[[Category: Frearson JA]] | |||
[[Category: Hui R]] | |||
[[Category: Hutchinson A]] | |||
[[Category: Kania A]] | |||
[[Category: Kozieradzki I]] | |||
[[Category: Lin Y-H]] | |||
[[Category: Qiu W]] | |||
[[Category: Ravichandran M]] | |||
[[Category: Robinson DA]] | |||
[[Category: Schapira M]] | |||
[[Category: Weigelt J]] | |||
[[Category: Wernimont A]] | |||
[[Category: Wyatt PG]] | |||
Latest revision as of 10:58, 6 September 2023
Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoACrystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA
Structural highlights
FunctionNMT1_HUMAN Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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