3ihj: Difference between revisions

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-{{Seed}}
-[[Image:3ihj.jpg|left|200px]]
-<!--
+==Human alanine aminotransferase 2 in complex with PLP==
-The line below this paragraph, containing "STRUCTURE_3ihj", creates the "Structure Box" on the page.
+<StructureSection load='3ihj' size='340' side='right'caption='[[3ihj]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3ihj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IHJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IHJ FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-{{STRUCTURE_3ihj|  PDB=3ihj  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ihj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ihj OCA], [https://pdbe.org/3ihj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ihj RCSB], [https://www.ebi.ac.uk/pdbsum/3ihj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ihj ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ALAT2_HUMAN ALAT2_HUMAN] Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate.<ref>PMID:11863375</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ih/3ihj_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ihj ConSurf].
+<div style="clear:both"></div>
-===Human alanine aminotransferase 2 in complex with PLP===
+==See Also==
+*[[Aminotransferase 3D structures|Aminotransferase 3D structures]]
+== References ==
-==About this Structure==
+<references/>
-IHJ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IHJ OCA].
+__TOC__
-[[Category: Alanine transaminase]]
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Arrowsmith, C H.]]
+[[Category: Large Structures]]
-[[Category: Berg, S Van Den.]]
+[[Category: Arrowsmith CH]]
-[[Category: Berglund, H.]]
+[[Category: Berglund H]]
-[[Category: Bountra, C.]]
+[[Category: Bountra C]]
-[[Category: Collins, R.]]
+[[Category: Collins R]]
-[[Category: Edwards, A M.]]
+[[Category: Edwards AM]]
-[[Category: Flodin, S.]]
+[[Category: Flodin S]]
-[[Category: Flores, A.]]
+[[Category: Flores A]]
-[[Category: Graslund, S.]]
+[[Category: Graslund S]]
-[[Category: Hammarstrom, M.]]
+[[Category: Hammarstrom M]]
-[[Category: Johansson, A.]]
+[[Category: Johansson A]]
-[[Category: Johansson, I.]]
+[[Category: Johansson I]]
-[[Category: Karlberg, T.]]
+[[Category: Karlberg T]]
-[[Category: Kotenyova, T.]]
+[[Category: Kotenyova T]]
-[[Category: Kotzsch, A.]]
+[[Category: Kotzsch A]]
-[[Category: Moche, M.]]
+[[Category: Moche M]]
-[[Category: Nielsen, T K.]]
+[[Category: Nielsen TK]]
-[[Category: Nordlund, P.]]
+[[Category: Nordlund P]]
-[[Category: Nyman, T.]]
+[[Category: Nyman T]]
-[[Category: Persson, C.]]
+[[Category: Persson C]]
-[[Category: Roos, A K.]]
+[[Category: Roos AK]]
-[[Category: SGC, Structural Genomics Consortium.]]
+[[Category: Schuler H]]
-[[Category: Schuler, H.]]
+[[Category: Schutz P]]
-[[Category: Schutz, P.]]
+[[Category: Siponen MI]]
-[[Category: Siponen, M I.]]
+[[Category: Svensson L]]
-[[Category: Svensson, L.]]
+[[Category: Thorsell AG]]
-[[Category: Thorsell, A G.]]
+[[Category: Tresaugues L]]
-[[Category: Tresaugues, L.]]
+[[Category: Van Den Berg S]]
-[[Category: Weigelt, J.]]
+[[Category: Weigelt J]]
-[[Category: Welin, M.]]
+[[Category: Welin M]]
-[[Category: Wisniewska, M.]]
+[[Category: Wisniewska M]]
-[[Category: Alternative splicing]]
-[[Category: Aminotransferase]]
-[[Category: Helix]]
-[[Category: Pyridoxal phosphate]]
-[[Category: Sgc]]
-[[Category: Structural genomic]]
-[[Category: Structural genomics consortium]]
-[[Category: Transferase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 19 13:43:52 2009''