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==Crystal structure of a cdpk kinase domain from cryptosporidium Parvum, cgd7_40== | ==Crystal structure of a cdpk kinase domain from cryptosporidium Parvum, cgd7_40== | ||
<StructureSection load='3hko' size='340' side='right' caption='[[3hko]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='3hko' size='340' side='right'caption='[[3hko]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3hko]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3hko]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HKO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HKO FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hko FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hko OCA], [https://pdbe.org/3hko PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hko RCSB], [https://www.ebi.ac.uk/pdbsum/3hko PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hko ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/Q5CZ29_CRYPI Q5CZ29_CRYPI] | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hk/3hko_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hk/3hko_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hko ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Calcium-dependent protein kinase|Calcium-dependent protein kinase]] | *[[Calcium-dependent protein kinase|Calcium-dependent protein kinase]] | ||
*[[Calcium/calmodulin dependent protein kinase 3D structures|Calcium/calmodulin dependent protein kinase 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Cryptosporidium parvum | [[Category: Cryptosporidium parvum Iowa II]] | ||
[[Category: Amani | [[Category: Large Structures]] | ||
[[Category: Arrowsmith | [[Category: Amani M]] | ||
[[Category: Artz | [[Category: Arrowsmith CH]] | ||
[[Category: Botchkarev | [[Category: Artz JD]] | ||
[[Category: Bountra | [[Category: Botchkarev A]] | ||
[[Category: Cossar | [[Category: Bountra C]] | ||
[[Category: Edwards | [[Category: Cossar D]] | ||
[[Category: Hui | [[Category: Edwards AM]] | ||
[[Category: Hutchinson | [[Category: Hui R]] | ||
[[Category: Kozieradzki | [[Category: Hutchinson A]] | ||
[[Category: MacKenzie | [[Category: Kozieradzki I]] | ||
[[Category: Vedadi | [[Category: MacKenzie F]] | ||
[[Category: Wasney | [[Category: Vedadi M]] | ||
[[Category: Weigelt | [[Category: Wasney G]] | ||
[[Category: Wernimont | [[Category: Weigelt J]] | ||
[[Category: Wernimont AK]] | |||
Latest revision as of 10:23, 6 September 2023
Crystal structure of a cdpk kinase domain from cryptosporidium Parvum, cgd7_40Crystal structure of a cdpk kinase domain from cryptosporidium Parvum, cgd7_40
Structural highlights
FunctionEvolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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