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==Crystal structure of the NI(II)-bound Glyoxalase-I from Clostridium acetobutylicum==
==Crystal structure of the NI(II)-bound Glyoxalase-I from Clostridium acetobutylicum==
<StructureSection load='3hdp' size='340' side='right' caption='[[3hdp]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
<StructureSection load='3hdp' size='340' side='right'caption='[[3hdp]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3hdp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_acetobutylicum Clostridium acetobutylicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HDP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HDP FirstGlance]. <br>
<table><tr><td colspan='2'>[[3hdp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_acetobutylicum Clostridium acetobutylicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HDP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HDP FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.06&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2qh0|2qh0]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CAC2192, CA_C2192 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1488 Clostridium acetobutylicum])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hdp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hdp OCA], [https://pdbe.org/3hdp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hdp RCSB], [https://www.ebi.ac.uk/pdbsum/3hdp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hdp ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lactoylglutathione_lyase Lactoylglutathione lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.5 4.4.1.5] </span></td></tr>
</table>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hdp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hdp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hdp RCSB], [http://www.ebi.ac.uk/pdbsum/3hdp PDBsum]</span></td></tr>
== Function ==
<table>
[https://www.uniprot.org/uniprot/Q97H22_CLOAB Q97H22_CLOAB]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hd/3hdp_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hd/3hdp_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hdp ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Glyoxalase|Glyoxalase]]
*[[Glyoxalase 3D structures|Glyoxalase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Clostridium acetobutylicum]]
[[Category: Clostridium acetobutylicum]]
[[Category: Lactoylglutathione lyase]]
[[Category: Large Structures]]
[[Category: Burley, S K.]]
[[Category: Burley SK]]
[[Category: Eswaramoorthy, S.]]
[[Category: Eswaramoorthy S]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics.]]
[[Category: Satyanarayana L]]
[[Category: Satyanarayana, L.]]
[[Category: Swaminathan S]]
[[Category: Swaminathan, S.]]
[[Category: 11003p]]
[[Category: Glutathione]]
[[Category: Glyoxalase]]
[[Category: Lyase]]
[[Category: Methylglyoxal]]
[[Category: New york sgx research center for structural genomic]]
[[Category: Nysgxrc.]]
[[Category: Protein structure initiative]]
[[Category: Psi2]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]

Latest revision as of 10:20, 6 September 2023

Crystal structure of the NI(II)-bound Glyoxalase-I from Clostridium acetobutylicumCrystal structure of the NI(II)-bound Glyoxalase-I from Clostridium acetobutylicum

Structural highlights

3hdp is a 1 chain structure with sequence from Clostridium acetobutylicum. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.06Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q97H22_CLOAB

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3hdp, resolution 2.06Å

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OCA