3gn4: Difference between revisions

<StructureSection load='3gn4' size='340' side='right'caption='[[3gn4]], [[Resolution|resolution]] 2.70&Aring;' scene=''>

<table><tr><td colspan='2'>[[3gn4]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster] and [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GN4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GN4 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gn4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gn4 OCA], [https://pdbe.org/3gn4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gn4 RCSB], [https://www.ebi.ac.uk/pdbsum/3gn4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gn4 ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/MYO6_PIG MYO6_PIG] Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Myosin 6 is a reverse-direction motor protein that moves towards the minus-end of actin filaments. Has slow rate of actin-activated ADP release due to weak ATP binding. Functions in a variety of intracellular processes such as vesicular membrane trafficking and cell migration. Required for the structural integrity of the Golgi apparatus via the p53-dependent pro-survival pathway. Appears to be involved in a very early step of clathrin-mediated endocytosis in polarized epithelial cells. May act as a regulator of F-actin dynamics. May play a role in transporting DAB2 from the plasma membrane to specific cellular targets. Required for structural integrity of inner ear hair cells (By similarity).<ref>PMID:16917816</ref>  

*[[Calmodulin 3D structures|Calmodulin 3D structures]]

*[[Myosin 3D Structures|Myosin 3D Structures]]

[[Category: Drosophila melanogaster]]

[[Category: Large Structures]]

[[Category: Sus scrofa]]

[[Category: Franzini-Armstrong C]]

[[Category: Houdusse A]]

[[Category: Kim H]]

[[Category: Llinas P]]

[[Category: Menetrey J]]

[[Category: Mukherjea M]]

[[Category: Safer D]]

[[Category: Selvin PR]]

[[Category: Sweeney HL]]

[[Category: Travaglia M]]

[[Category: Zong AB]]