3fm3: Difference between revisions

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 ==Crystal structure of an Encephalitozoon cuniculi methionine aminopeptidase type 2==
-<StructureSection load='3fm3' size='340' side='right' caption='[[3fm3]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
+<StructureSection load='3fm3' size='340' side='right'caption='[[3fm3]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3fm3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enccn Enccn]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2nw5 2nw5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FM3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FM3 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3fm3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Encephalitozoon_cuniculi Encephalitozoon cuniculi]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2nw5 2nw5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FM3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FM3 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.18&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3fmq|3fmq]], [[3fmr|3fmr]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ECU10_0750, MAP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6035 ENCCN])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fm3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fm3 OCA], [https://pdbe.org/3fm3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fm3 RCSB], [https://www.ebi.ac.uk/pdbsum/3fm3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fm3 ProSAT]</span></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionyl_aminopeptidase Methionyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.18 3.4.11.18] </span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fm3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fm3 OCA], [http://pdbe.org/3fm3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fm3 RCSB], [http://www.ebi.ac.uk/pdbsum/3fm3 PDBsum]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/AMPM2_ENCCU AMPM2_ENCCU]] Removes the N-terminal methionine from nascent proteins.
+[https://www.uniprot.org/uniprot/MAP2_ENCCU MAP2_ENCCU] Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).[HAMAP-Rule:MF_03175]<ref>PMID:14736176</ref> <ref>PMID:16004378</ref> <ref>PMID:16917013</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fm/3fm3_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fm/3fm3_consurf.spt"</scriptWhenChecked>
      <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
@@ Line 32: / Line 31: @@
 ==See Also==
-*[[Aminopeptidase|Aminopeptidase]]
+*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Enccn]]
-[[Category: Methionyl aminopeptidase]]
-[[Category: Adams, J]]
-[[Category: Almo, S C]]
-[[Category: Alvarado, J J]]
-[[Category: Burley, S K]]
-[[Category: Structural genomic]]
-[[Category: Russell, M]]
-[[Category: Toro, R]]
-[[Category: Weiss, L M]]
-[[Category: Zhang, A]]
-[[Category: Aminopeptidase]]
-[[Category: Cobalt]]
 [[Category: Encephalitozoon cuniculi]]
-[[Category: Hydrolase]]
+[[Category: Large Structures]]
-[[Category: Metal-binding]]
+[[Category: Adams J]]
-[[Category: Metap2]]
+[[Category: Almo SC]]
-[[Category: Methionine aminopeptidase type2]]
+[[Category: Alvarado JJ]]
-[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
+[[Category: Burley SK]]
-[[Category: Protease]]
+[[Category: Russell M]]
-[[Category: PSI, Protein structure initiative]]
+[[Category: Toro R]]
+[[Category: Weiss LM]]
+[[Category: Zhang A]]