5ipe: Difference between revisions

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==Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) nucleoside thiophosphoramidate catalytic product complex==
==Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) nucleoside thiophosphoramidate catalytic product complex==
<StructureSection load='5ipe' size='340' side='right' caption='[[5ipe]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
<StructureSection load='5ipe' size='340' side='right'caption='[[5ipe]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ipe]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IPE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IPE FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ipe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IPE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IPE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6CG:5-S-PHOSPHONO-5-THIOGUANOSINE'>6CG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1kpa|1kpa]], [[3tw2|3tw2]], [[5i2e|5i2e]], [[5i2f|5i2f]], [[4eqe|4eqe]], [[4eqg|4eqg]], [[4eqh|4eqh]], [[5ipb|5ipb]], [[5ipc|5ipc]], [[5ipd|5ipd]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6CG:5-S-PHOSPHONO-5-THIOGUANOSINE'>6CG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HINT1, HINT, PKCI1, PRKCNH1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ipe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ipe OCA], [https://pdbe.org/5ipe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ipe RCSB], [https://www.ebi.ac.uk/pdbsum/5ipe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ipe ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ipe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ipe OCA], [http://pdbe.org/5ipe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ipe RCSB], [http://www.ebi.ac.uk/pdbsum/5ipe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ipe ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/HINT1_HUMAN HINT1_HUMAN]] Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2 (By similarity).  
[https://www.uniprot.org/uniprot/HINT1_HUMAN HINT1_HUMAN] Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2 (By similarity).
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
<div class="pdbe-citations 5ipe" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5ipe" style="background-color:#fffaf0;"></div>
==See Also==
*[[Histidine triad nucleotide-binding protein 3D structures|Histidine triad nucleotide-binding protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Finzel, B C]]
[[Category: Large Structures]]
[[Category: Maize, K M]]
[[Category: Finzel BC]]
[[Category: Hint]]
[[Category: Maize KM]]
[[Category: Histidine triad]]
[[Category: Hit]]
[[Category: Hydrolase]]

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