5id7: Difference between revisions

<StructureSection load='5id7' size='340' side='right'caption='[[5id7]], [[Resolution|resolution]] 2.26&Aring;' scene=''>

<table><tr><td colspan='2'>[[5id7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ID7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ID7 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.26&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6A4:(4S)-2-SULFANYLIDENE-4-[(TETRADECANOYLOXY)METHYL]-1,3,2LAMBDA~5~-DIOXAPHOSPHOLANE-2-THIOLATE'>6A4</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5id7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5id7 OCA], [https://pdbe.org/5id7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5id7 RCSB], [https://www.ebi.ac.uk/pdbsum/5id7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5id7 ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN] Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:[https://omim.org/entry/103600 103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.<ref>PMID:8048949</ref> <ref>PMID:7852505</ref> <ref>PMID:9329347</ref> <ref>PMID:9589637</ref>  

[https://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref>  

[[Category: Bujacz A]]

[[Category: Bujacz G]]

[[Category: Rytczak P]]

[[Category: Sekula B]]