3eb3: Difference between revisions

No edit summary
No edit summary
 
(2 intermediate revisions by the same user not shown)
Line 1: Line 1:
==Voltage-dependent K+ channel beta subunit (W121A) in complex with cortisone==
==Voltage-dependent K+ channel beta subunit (W121A) in complex with cortisone==
<StructureSection load='3eb3' size='340' side='right' caption='[[3eb3]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='3eb3' size='340' side='right'caption='[[3eb3]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3eb3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EB3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EB3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3eb3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EB3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EB3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=PDN:17,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE'>PDN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1qrq|1qrq]], [[1exb|1exb]], [[3eau|3eau]], [[3eb4|3eb4]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=PDN:17,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE'>PDN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Kcnab2, Ckbeta2, Kcnb3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3eb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eb3 OCA], [https://pdbe.org/3eb3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3eb3 RCSB], [https://www.ebi.ac.uk/pdbsum/3eb3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3eb3 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3eb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eb3 OCA], [http://pdbe.org/3eb3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3eb3 RCSB], [http://www.ebi.ac.uk/pdbsum/3eb3 PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/KCAB2_RAT KCAB2_RAT]] Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit.  
[https://www.uniprot.org/uniprot/KCAB2_RAT KCAB2_RAT] Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eb/3eb3_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eb/3eb3_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
Line 31: Line 31:


==See Also==
==See Also==
*[[Potassium Channel|Potassium Channel]]
*[[Potassium channel 3D structures|Potassium channel 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Buffalo rat]]
[[Category: Large Structures]]
[[Category: Bhosle, R C]]
[[Category: Rattus norvegicus]]
[[Category: Cao, Y]]
[[Category: Bhosle RC]]
[[Category: Kabaleeswaran, V]]
[[Category: Cao Y]]
[[Category: Li, H]]
[[Category: Kabaleeswaran V]]
[[Category: Pan, Y]]
[[Category: Li H]]
[[Category: Weng, J]]
[[Category: Pan Y]]
[[Category: Zhou, M]]
[[Category: Weng J]]
[[Category: Cortisone]]
[[Category: Zhou M]]
[[Category: Interface]]
[[Category: Ion transport]]
[[Category: Ionic channel]]
[[Category: Kvbeta]]
[[Category: Nadp]]
[[Category: Oxidoreductase]]
[[Category: Phosphoprotein]]
[[Category: Potassium]]
[[Category: Potassium transport]]
[[Category: Transport]]
[[Category: Transport protein]]
[[Category: Voltage-gated channel]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA