3e77: Difference between revisions

<StructureSection load='3e77' size='340' side='right'caption='[[3e77]], [[Resolution|resolution]] 2.50&Aring;' scene=''>

<table><tr><td colspan='2'>[[3e77]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E77 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3E77 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3e77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e77 OCA], [https://pdbe.org/3e77 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3e77 RCSB], [https://www.ebi.ac.uk/pdbsum/3e77 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3e77 ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/SERC_HUMAN SERC_HUMAN] Defects in PSAT1 are the cause of phosphoserine aminotransferase deficiency (PSATD) [MIM:[https://omim.org/entry/610992 610992]. PSATD is characterized biochemically by low plasma and cerebrospinal fluid concentrations of serine and glycine and clinically by intractable seizures, acquired microcephaly, hypertonia, and psychomotor retardation.<ref>PMID:17436247</ref>  

[https://www.uniprot.org/uniprot/SERC_HUMAN SERC_HUMAN] Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine (By similarity).

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Andersson J]]

[[Category: Arrowsmith CH]]

[[Category: Berglund H]]

[[Category: Bountra C]]

[[Category: Collins R]]

[[Category: Dahlgren LG]]

[[Category: Edwards AM]]

[[Category: Flodin S]]

[[Category: Flores A]]

[[Category: Graslund S]]

[[Category: Hammarstrom M]]

[[Category: Johansson A]]

[[Category: Johansson I]]

[[Category: Karlberg T]]

[[Category: Kotenyova T]]

[[Category: Lehtio L]]

[[Category: Moche M]]

[[Category: Nilsson ME]]

[[Category: Nordlund P]]

[[Category: Nyman T]]

[[Category: Olesen K]]

[[Category: Persson C]]

[[Category: Sagemark J]]

[[Category: Schueler H]]

[[Category: Thorsell SG]]

[[Category: Tresaugues L]]

[[Category: Van Den Berg S]]

[[Category: Weigelt J]]

[[Category: Welin M]]

[[Category: Wikstrom M]]

[[Category: Wisniewska M]]