3dn4: Difference between revisions
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<StructureSection load='3dn4' size='340' side='right'caption='[[3dn4]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='3dn4' size='340' side='right'caption='[[3dn4]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3dn4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[3dn4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DN4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DN4 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene>, <scene name='pdbligand=PIH:IODOPHENYL'>PIH</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dn4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dn4 OCA], [https://pdbe.org/3dn4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dn4 RCSB], [https://www.ebi.ac.uk/pdbsum/3dn4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dn4 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dn4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dn4 OCA], [https://pdbe.org/3dn4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dn4 RCSB], [https://www.ebi.ac.uk/pdbsum/3dn4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dn4 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Escherichia virus T4]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Liu L]] | |||
[[Category: Liu | [[Category: Matthews BW]] | ||
[[Category: Matthews | |||