3dm0: Difference between revisions

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==Maltose Binding Protein fusion with RACK1 from A. thaliana==
==Maltose Binding Protein fusion with RACK1 from A. thaliana==
<StructureSection load='3dm0' size='340' side='right' caption='[[3dm0]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='3dm0' size='340' side='right'caption='[[3dm0]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3dm0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DM0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DM0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3dm0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana] and [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DM0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DM0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">malE, b4034, JW3994,ARCA, At1g18080, T10F20.9, T10O22.6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900001:alpha-maltose'>PRD_900001</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dm0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dm0 OCA], [http://pdbe.org/3dm0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3dm0 RCSB], [http://www.ebi.ac.uk/pdbsum/3dm0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3dm0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dm0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dm0 OCA], [https://pdbe.org/3dm0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dm0 RCSB], [https://www.ebi.ac.uk/pdbsum/3dm0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dm0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MALE_ECOLI MALE_ECOLI]] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.  
[https://www.uniprot.org/uniprot/MALE_ECOLI MALE_ECOLI] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.[https://www.uniprot.org/uniprot/GBLPA_ARATH GBLPA_ARATH] Major component of the RACK1 regulatory proteins that play a role in multiple signal transduction pathways. Involved in multiple hormone responses and developmental processes (PubMed:16829549, PubMed:18715992, PubMed:18947417). MAPK cascade scaffolding protein involved in the protease IV and ArgC signaling pathway but not the flg22 pathway (PubMed:25731164).<ref>PMID:16829549</ref> <ref>PMID:18715992</ref> <ref>PMID:18947417</ref> <ref>PMID:25731164</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dm/3dm0_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dm/3dm0_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Arath]]
[[Category: Arabidopsis thaliana]]
[[Category: Armstrong, D L]]
[[Category: Escherichia coli K-12]]
[[Category: Moon, A F]]
[[Category: Large Structures]]
[[Category: Pedersen, L C]]
[[Category: Armstrong DL]]
[[Category: Scappini, E L]]
[[Category: Moon AF]]
[[Category: Ullah, H]]
[[Category: Pedersen LC]]
[[Category: Williams, L V]]
[[Category: Scappini EL]]
[[Category: Beta-propeller wd40 repeat]]
[[Category: Ullah H]]
[[Category: Mbp rack1a]]
[[Category: Williams LV]]
[[Category: Receptor for activiated protein c-kinase 1]]
[[Category: Signaling protein]]
[[Category: Sugar binding protein]]
[[Category: Sugar transport]]
[[Category: Transport]]
[[Category: Wd repeat]]

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