3da2: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-{{Seed}}
-[[Image:3da2.png|left|200px]]
-<!--
+==X-ray structure of human carbonic anhydrase 13 in complex with inhibitor==
-The line below this paragraph, containing "STRUCTURE_3da2", creates the "Structure Box" on the page.
+<StructureSection load='3da2' size='340' side='right'caption='[[3da2]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3da2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DA2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DA2 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4MD:N-(4-CHLOROBENZYL)-N-METHYLBENZENE-1,4-DISULFONAMIDE'>4MD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-{{STRUCTURE_3da2|  PDB=3da2  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3da2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3da2 OCA], [https://pdbe.org/3da2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3da2 RCSB], [https://www.ebi.ac.uk/pdbsum/3da2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3da2 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/CAH13_HUMAN CAH13_HUMAN] Reversible hydration of carbon dioxide.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/da/3da2_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3da2 ConSurf].
+<div style="clear:both"></div>
-===X-ray structure of human carbonic anhydrase 13 in complex with inhibitor===
+==See Also==
+*[[Carbonic anhydrase 3D structures|Carbonic anhydrase 3D structures]]
+__TOC__
-==About this Structure==
+</StructureSection>
-DA2 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DA2 OCA].
-[[Category: Carbonate dehydratase]]
 [[Category: Homo sapiens]]
-[[Category: Arrowsmith, C H.]]
+[[Category: Large Structures]]
-[[Category: Bountra, C.]]
+[[Category: Arrowsmith CH]]
-[[Category: Bray, J E.]]
+[[Category: Bountra C]]
-[[Category: Delft, F von.]]
+[[Category: Bray JE]]
-[[Category: Edwards, A M.]]
+[[Category: Edwards AM]]
-[[Category: Filippakopoulos, P.]]
+[[Category: Filippakopoulos P]]
-[[Category: King, O N.F.]]
+[[Category: King ONF]]
-[[Category: Oppermann, U.]]
+[[Category: Oppermann U]]
-[[Category: Picaud, S S.]]
+[[Category: Picaud SS]]
-[[Category: Pike, A C.W.]]
+[[Category: Pike ACW]]
-[[Category: Pilka, E S.]]
+[[Category: Pilka ES]]
-[[Category: Roos, A K.]]
+[[Category: Roos AK]]
-[[Category: SGC, Structural Genomics Consortium.]]
+[[Category: Wikstrom M]]
-[[Category: Wikstrom, M.]]
+[[Category: Yue WW]]
-[[Category: Yue, W W.]]
+[[Category: Von Delft F]]
-[[Category: Carbonic anhydrase]]
-[[Category: Lyase]]
-[[Category: Metal-binding]]
-[[Category: Sgc]]
-[[Category: Structural genomic]]
-[[Category: Structural genomics consortium]]
-[[Category: Sulfonamide]]
-[[Category: Zinc]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 19:00:34 2009''