3d9y: Difference between revisions
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==Crystal Structure of Profilin from Schizosaccharomyces pombe== | ==Crystal Structure of Profilin from Schizosaccharomyces pombe== | ||
<StructureSection load='3d9y' size='340' side='right' caption='[[3d9y]], [[Resolution|resolution]] 1.65Å' scene=''> | <StructureSection load='3d9y' size='340' side='right'caption='[[3d9y]], [[Resolution|resolution]] 1.65Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3d9y]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3d9y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D9Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D9Y FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d9y OCA], [https://pdbe.org/3d9y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d9y RCSB], [https://www.ebi.ac.uk/pdbsum/3d9y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d9y ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/PROF_SCHPO PROF_SCHPO] Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. In S.pombe, it is essential for cytokinesis. | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 3d9y" style="background-color:#fffaf0;"></div> | |||
==See Also== | |||
*[[Profilin 3D Structures|Profilin 3D Structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Schizosaccharomyces pombe]] | [[Category: Schizosaccharomyces pombe]] | ||
[[Category: Ezezika | [[Category: Ezezika OC]] | ||
[[Category: Nolen | [[Category: Nolen BJ]] | ||
[[Category: Pollard | [[Category: Pollard TD]] | ||